Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DA000541-23
Application #
2116402
Study Section
Special Emphasis Panel (NSS)
Project Start
1975-06-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
23
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Emory University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
042250712
City
Atlanta
State
GA
Country
United States
Zip Code
30322

  Publications

Joyce, Andrew R; Easterling, Keith; Holtzman, Stephen G et al. (2006) Modeling the onset of drug dependence: a consideration of the requirement for protein synthesis. J Theor Biol 240:531-7
White, David A; Hwang, M Lisa; Holtzman, Stephen G (2005) Naltrexone-induced conditioned place aversion following a single dose of morphine in the rat. Pharmacol Biochem Behav 81:451-8
White, David A; Holtzman, Stephen G (2005) Periadolescent morphine exposure alters subsequent behavioral sensitivity to morphine in adult rats. Eur J Pharmacol 528:119-23
White, David A; Holtzman, Stephen G (2005) Discriminative stimulus effects of acute morphine followed by naltrexone in the squirrel monkey: a further characterization. J Pharmacol Exp Ther 314:374-82
Easterling, Keith W; Holtzman, Stephen G (2004) In rats, acute morphine dependence results in antagonist-induced response suppression of intracranial self-stimulation. Psychopharmacology (Berl) 175:287-95
White, David A; Holtzman, Stephen G (2003) Discriminative stimulus effects of acute morphine followed by naltrexone in the squirrel monkey. Psychopharmacology (Berl) 167:203-10
Holtzman, Stephen G (2003) Discrimination of a single dose of morphine followed by naltrexone: substitution of other agonists for morphine and other antagonists for naltrexone in a rat model of acute dependence. J Pharmacol Exp Ther 304:1033-41
Kalinichev, Mikhail; Holtzman, Stephen G (2003) Changes in urination/defecation, auditory startle response, and startle-induced ultrasonic vocalizations in rats undergoing morphine withdrawal: similarities and differences between acute and chronic dependence. J Pharmacol Exp Ther 304:603-9
Schad, Christina A; Justice Jr, Joseph B; Holtzman, Stephen G (2002) Endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions. J Pharmacol Exp Ther 300:932-8
Powell, K R; Holtzman, S G (2001) Parametric evaluation of the development of sensitization to the effects of morphine on locomotor activity. Drug Alcohol Depend 62:83-90

Showing the most recent 10 out of 98 publications