Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37DA004077-07
Application #
3482686
Study Section
Drug Abuse Biomedical Research Review Committee (DABR)
Project Start
1987-07-01
Project End
1998-06-30
Budget Start
1993-07-01
Budget End
1994-06-30
Support Year
7
Fiscal Year
1993
Total Cost
Indirect Cost

  Institution

Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030

  Publications

Wooltorton, Julian R A; Pidoplichko, Volodymyr I; Broide, Ron S et al. (2003) Differential desensitization and distribution of nicotinic acetylcholine receptor subtypes in midbrain dopamine areas. J Neurosci 23:3176-85
Franceschini, Davide; Paylor, Richard; Broide, Ron et al. (2002) Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures. Brain Res Mol Brain Res 98:29-40
Broide, R S; Orr-Urtreger, A; Patrick, J W (2001) Normal apoptosis levels in mice expressing one alpha7 nicotinic receptor null and one L250T mutant allele. Neuroreport 12:1643-8
Orr-Urtreger, A; Broide, R S; Kasten, M R et al. (2000) Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth. J Neurochem 74:2154-66
Xu, W; Gelber, S; Orr-Urtreger, A et al. (1999) Megacystis, mydriasis, and ion channel defect in mice lacking the alpha3 neuronal nicotinic acetylcholine receptor. Proc Natl Acad Sci U S A 96:5746-51
Chen, D; Dang, H; Patrick, J W (1998) Contributions of N-linked glycosylation to the expression of a functional alpha7-nicotinic receptor in Xenopus oocytes. J Neurochem 70:349-57
Chen, D; Patrick, J W (1997) The alpha-bungarotoxin-binding nicotinic acetylcholine receptor from rat brain contains only the alpha7 subunit. J Biol Chem 272:24024-9
Goldner, F M; Dineley, K T; Patrick, J W (1997) Immunohistochemical localization of the nicotinic acetylcholine receptor subunit alpha6 to dopaminergic neurons in the substantia nigra and ventral tegmental area. Neuroreport 8:2739-42
Orr-Urtreger, A; Goldner, F M; Saeki, M et al. (1997) Mice deficient in the alpha7 neuronal nicotinic acetylcholine receptor lack alpha-bungarotoxin binding sites and hippocampal fast nicotinic currents. J Neurosci 17:9165-71
Colquhoun, L M; Patrick, J W (1997) Pharmacology of neuronal nicotinic acetylcholine receptor subtypes. Adv Pharmacol 39:191-220

Showing the most recent 10 out of 16 publications