Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DA006303-14
Application #
6580874
Study Section
Special Emphasis Panel (NSS)
Program Officer
Kline, Richard
Project Start
1989-09-30
Project End
2008-02-29
Budget Start
2003-03-01
Budget End
2004-02-29
Support Year
14
Fiscal Year
2003
Total Cost
$380,250
Indirect Cost

  Institution

Name
Harvard University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
047006379
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Torun, Lokman; Madras, Bertha K; Meltzer, Peter C (2012) Synthesis and structure-activity relationship studies of 3-biaryl-8-oxabicyclo[3.2.1]octane-2-carboxylic acid methyl esters. Bioorg Med Chem 20:2762-72
Purushotham, Madhusudhan; Sheri, Anjaneyulu; Pham-Huu, Duy-Phong et al. (2011) The synthesis and biological evaluation of 2-(3-methyl or 3-phenylisoxazol-5-yl)-3-aryl-8-thiabicyclo[3.2.1]octanes. Bioorg Med Chem Lett 21:48-51
Vallender, Eric J; Lynch, Laurie; Novak, Melinda A et al. (2009) Polymorphisms in the 3' UTR of the serotonin transporter are associated with cognitive flexibility in rhesus macaques. Am J Med Genet B Neuropsychiatr Genet 150B:467-75
Vallender, E J; Priddy, C M; Hakim, S et al. (2008) Functional variation in the 3'untranslated region of the serotonin transporter in human and rhesus macaque. Genes Brain Behav 7:690-7
Xie, Zhihua; Miller, Gregory M (2008) Beta-phenylethylamine alters monoamine transporter function via trace amine-associated receptor 1: implication for modulatory roles of trace amines in brain. J Pharmacol Exp Ther 325:617-28
Xie, Zhihua; Vallender, Eric J; Yu, Naichen et al. (2008) Cloning, expression, and functional analysis of rhesus monkey trace amine-associated receptor 6: evidence for lack of monoaminergic association. J Neurosci Res 86:3435-46
Verrico, Christopher D; Lynch, Laurie; Fahey, Michele A et al. (2008) MDMA-induced impairment in primates: antagonism by a selective norepinephrine or serotonin, but not by a dopamine/norepinephrine transport inhibitor. J Psychopharmacol 22:187-202
Vallender, Eric J; Priddy, Cassandra M; Chen, Guo-Lin et al. (2008) Human expression variation in the mu-opioid receptor is paralleled in rhesus macaque. Behav Genet 38:390-5
Xie, Zhihua; Westmoreland, Susan V; Miller, Gregory M (2008) Modulation of monoamine transporters by common biogenic amines via trace amine-associated receptor 1 and monoamine autoreceptors in human embryonic kidney 293 cells and brain synaptosomes. J Pharmacol Exp Ther 325:629-40
Xie, Zhihua; Westmoreland, Susan V; Bahn, Mary E et al. (2007) Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro. J Pharmacol Exp Ther 321:116-27

Showing the most recent 10 out of 73 publications