Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37DE003420-17
Application #
3482718
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1976-02-01
Project End
1995-06-30
Budget Start
1990-07-01
Budget End
1991-06-30
Support Year
17
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Forsyth Institute
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02142
Movila, Alexandru; Kajiya, Mikihito; Wisitrasameewong, Wichaya et al. (2018) Intravital endoscopic technology for real-time monitoring of inflammation caused in experimental periodontitis. J Immunol Methods 457:26-29
Kanzaki, Hiroyuki; Movila, Alexandru; Kayal, Rayyan et al. (2017) Phosphoglycerol dihydroceramide, a distinctive ceramide produced by Porphyromonas gingivalis, promotes RANKL-induced osteoclastogenesis by acting on non-muscle myosin II-A (Myh9), an osteoclast cell fusion regulatory factor. Biochim Biophys Acta Mol Cell Biol Lipids 1862:452-462
Kanzaki, Hiroyuki; Shinohara, Fumiaki; Suzuki, Maiko et al. (2016) A-Disintegrin and Metalloproteinase (ADAM) 17 Enzymatically Degrades Interferon-gamma. Sci Rep 6:32259
Matsuda, Shinji; Movila, Alexandru; Suzuki, Maiko et al. (2016) A novel method of sampling gingival crevicular fluid from a mouse model of periodontitis. J Immunol Methods 438:21-25
Lin, Jiang; Bi, Liangjia; Yu, Xiaoqian et al. (2014) Porphyromonas gingivalis exacerbates ligature-induced, RANKL-dependent alveolar bone resorption via differential regulation of Toll-like receptor 2 (TLR2) and TLR4. Infect Immun 82:4127-34
Han, Xiaozhe; LaRosa, Karen B; Kawai, Toshihisa et al. (2014) DNA-based adaptive immunity protect host from infection-associated periodontal bone resorption via recognition of Porphyromonas gingivalis virulence component. Vaccine 32:297-303
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Yu, Xiaoqian; Lin, Jiang; Yu, Qing et al. (2014) Activation of Toll?like receptor 9 inhibits lipopolysaccharide?induced receptor activator of nuclear factor kappa? B ligand expression in rat B lymphocytes. Microbiol Immunol 58:51-60
Han, Xiaozhe; Lin, Xiaoping; Yu, Xiaoqian et al. (2013) Porphyromonas gingivalis infection-associated periodontal bone resorption is dependent on receptor activator of NF-?B ligand. Infect Immun 81:1502-9
Silva, Marcelo J B; Kajiya, Mikihito; AlShwaimi, Emad et al. (2012) Bacteria-reactive immune response may induce RANKL-expressing T cells in the mouse periapical bone loss lesion. J Endod 38:346-50

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