Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DE003739-24
Application #
2128926
Study Section
Oral Biology and Medicine Subcommittee 1 (OBM)
Project Start
1976-06-01
Project End
2000-06-30
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
24
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Southern California
Department
Dentistry
Type
Schools of Dentistry
DUNS #
041544081
City
Los Angeles
State
CA
Country
United States
Zip Code
90089
Devulapalle, K S; Mooser, G (2001) Glucosyltransferase inactivation reduces dental caries. J Dent Res 80:466-9
Devulapalle, K S; Mooser, G (2000) Subsite specificity of divalent metal ions to glucosyltransferase. J Craniofac Genet Dev Biol 20:107-8
Devulapalle, K S; Goodman, S D; Gao, Q et al. (1997) Knowledge-based model of a glucosyltransferase from the oral bacterial group of mutans streptococci. Protein Sci 6:2489-93
Devulapalle, K S; Mooser, G (1994) Subsite specificity of the active site of glucosyltransferases from Streptococcus sobrinus. J Biol Chem 269:11967-71
Cope, P A; Mooser, G (1993) Antibodies against active-site peptides common to glucosyltransferases of mutans streptococci. Infect Immun 61:4814-7
Mooser, G; Hefta, S A; Paxton, R J et al. (1991) Isolation and sequence of an active-site peptide containing a catalytic aspartic acid from two Streptococcus sobrinus alpha-glucosyltransferases. J Biol Chem 266:8916-22
Wong, C; Hefta, S A; Paxton, R J et al. (1990) Size and subdomain architecture of the glucan-binding domain of sucrose:3-alpha-D-glucosyltransferase from Streptococcus sobrinus. Infect Immun 58:2165-70
Mooser, G; Iwaoka, K R (1989) Sucrose 6-alpha-D-glucosyltransferase from Streptococcus sobrinus: characterization of a glucosyl-enzyme complex. Biochemistry 28:443-9
Mooser, G; Wong, C (1988) Isolation of a glucan-binding domain of glucosyltransferase (1,6-alpha-glucan synthase) from Streptococcus sobrinus. Infect Immun 56:880-4
Mooser, G; Shur, D; Lyou, M et al. (1985) Kinetic studies on dextransucrase from the cariogenic oral bacterium Streptococcus mutans. J Biol Chem 260:6907-15