Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DE003987-22
Application #
2128934
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Dentistry
Type
Schools of Dentistry
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Lee, Hsi-Ming; Ciancio, Sebastian G; Tuter, Gulay et al. (2004) Subantimicrobial dose doxycycline efficacy as a matrix metalloproteinase inhibitor in chronic periodontitis patients is enhanced when combined with a non-steroidal anti-inflammatory drug. J Periodontol 75:453-63
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Golub, L M; Ramamurthy, N S; Llavaneras, A et al. (1999) A chemically modified nonantimicrobial tetracycline (CMT-8) inhibits gingival matrix metalloproteinases, periodontal breakdown, and extra-oral bone loss in ovariectomized rats. Ann N Y Acad Sci 878:290-310
Llavaneras, A; Golub, L M; Rifkin, B R et al. (1999) CMT-8/clodronate combination therapy synergistically inhibits alveolar bone loss in LPS-induced periodontitis. Ann N Y Acad Sci 878:671-4
Sasaki, T; Ohyori, N; Debari, K et al. (1999) Effects of chemically modified tetracycline, CMT-8, on bone loss and osteoclast structure and function in osteoporotic states. Ann N Y Acad Sci 878:347-60

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