Agency
National Institute of Health (NIH)
Institute
National Institute of Dental & Craniofacial Research (NIDCR)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37DE008108-10
Application #
2544375
Study Section
Special Emphasis Panel (ZRG4-GMA-1 (02))
Project Start
1986-09-01
Project End
2001-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Rochester
Department
Dentistry
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627
Ten Hagen, Kelly G; Balys, Marlene M; Tabak, Lawrence A et al. (2002) Analysis of isoproterenol-induced changes in parotid gland gene expression. Physiol Genomics 8:107-14
Ten Hagen, K G; Bedi, G S; Tetaert, D et al. (2001) Cloning and characterization of a ninth member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family, ppGaNTase-T9. J Biol Chem 276:17395-404
Kingsley, P D; Hagen, K G; Maltby, K M et al. (2000) Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology 10:1317-23
Ten Hagen, K G; Tetaert, D; Hagen, F K et al. (1999) Characterization of a UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase that displays glycopeptide N-acetylgalactosaminyltransferase activity. J Biol Chem 274:27867-74
Hagen, F K; Hazes, B; Raffo, R et al. (1999) Structure-function analysis of the UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase. Essential residues lie in a predicted active site cleft resembling a lactose repressor fold. J Biol Chem 274:6797-803
Hagen, F K; Nehrke, K (1998) cDNA cloning and expression of a family of UDP-N-acetyl-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase sequence homologs from Caenorhabditis elegans. J Biol Chem 273:8268-77
Nehrke, K; Hagen, F K; Tabak, L A (1998) Isoform-specific O-glycosylation by murine UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-T3, in vivo. Glycobiology 8:367-71
Ten Hagen, K G; Hagen, F K; Balys, M M et al. (1998) Cloning and expression of a novel, tissue specifically expressed member of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family. J Biol Chem 273:27749-54
Nehrke, K; Ten Hagen, K G; Hagen, F K et al. (1997) Charge distribution of flanking amino acids inhibits O-glycosylation of several single-site acceptors in vivo. Glycobiology 7:1053-60
Nehrke, K; Tabak, L A (1997) Biosynthesis of a low-molecular-mass rat submandibular gland mucin glycoprotein in COS7 cells. Biochem J 323 ( Pt 2):497-502

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