Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK012413-30
Application #
2015944
Study Section
Special Emphasis Panel (NSS)
Project Start
1991-09-30
Project End
1997-04-30
Budget Start
1996-09-30
Budget End
1997-04-30
Support Year
30
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Loh, E; Rebbeck, T R; Mahoney, P D et al. (1999) Common variant in AMPD1 gene predicts improved clinical outcome in patients with heart failure. Circulation 99:1422-5
Hisatome, I; Morisaki, T; Kamma, H et al. (1998) Control of AMP deaminase 1 binding to myosin heavy chain. Am J Physiol 275:C870-81
Morisaki, H; Morisaki, T; Newby, L K et al. (1993) Alternative splicing: a mechanism for phenotypic rescue of a common inherited defect. J Clin Invest 91:2275-80
Morisaki, T; Holmes, E W (1993) Functionally distinct elements are required for expression of the AMPD1 gene in myocytes. Mol Cell Biol 13:5854-60
Morisaki, T; Gross, M; Morisaki, H et al. (1992) Molecular basis of AMP deaminase deficiency in skeletal muscle. Proc Natl Acad Sci U S A 89:6457-61
Sabina, R L; Fishbein, W N; Pezeshkpour, G et al. (1992) Molecular analysis of the myoadenylate deaminase deficiencies. Neurology 42:170-9
Mineo, I; Clarke, P R; Sabina, R L et al. (1990) A novel pathway for alternative splicing: identification of an RNA intermediate that generates an alternative 5' splice donor site not present in the primary transcript of AMPD1. Mol Cell Biol 10:5271-8
Moseley, W S; Morisaki, T; Sabina, R L et al. (1990) Ampd-2 maps to distal mouse chromosome 3 in linkage with Ampd-1. Genomics 6:572-4
Morisaki, T; Sabina, R L; Holmes, E W (1990) Adenylate deaminase. A multigene family in humans and rats. J Biol Chem 265:11482-6
Sabina, R L; Morisaki, T; Clarke, P et al. (1990) Characterization of the human and rat myoadenylate deaminase genes. J Biol Chem 265:9423-33

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