Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
3R37DK018171-20S1
Application #
2137162
Study Section
Physiological Chemistry Study Section (PC)
Project Start
1978-02-01
Project End
1996-11-30
Budget Start
1994-02-01
Budget End
1996-11-30
Support Year
20
Fiscal Year
1995
Total Cost
Indirect Cost
Name
State University New York Stony Brook
Department
Pharmacology
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Margot, J B; Williams, D L (1996) Estrogen induces the assembly of a multiprotein messenger ribonucleoprotein complex on the 3'-untranslated region of chicken apolipoprotein II mRNA. J Biol Chem 271:4452-60
Sensel, M G; Binder, R; Lazier, C B et al. (1994) Reactivation of apolipoprotein II gene transcription by cycloheximide reveals two steps in the deactivation of estrogen receptor-mediated transcription. Mol Cell Biol 14:1733-42
MacDonald, C C; Williams, D L (1993) RNase H/oligonucleotide-directed mRNA purification (ROMP) of apoll mRNA. Nucleic Acids Res 21:765-6
MacDonald, C C; Williams, D L (1992) Proteins associated with the messenger ribonucleoprotein particle for the estrogen-regulated apolipoprotein II mRNA. Biochemistry 31:1742-8
Nicosia, M; Prack, M M; Williams, D L (1992) Differential regulation of apolipoprotein-E messenger RNA in zona fasciculata cells of rat adrenal gland determined by in situ hybridization. Mol Endocrinol 6:288-98
Nicosia, M; Moger, W H; Dyer, C A et al. (1992) Apolipoprotein-E messenger RNA in rat ovary is expressed in theca and interstitial cells and presumptive macrophage, but not in granulosa cells. Mol Endocrinol 6:978-88
Prack, M M; Nicosia, M; Williams, D L et al. (1991) Relationship between apolipoprotein E mRNA expression and tissue cholesterol content in rat adrenal gland. J Lipid Res 32:1611-8
Binder, R; Gordon, D A; Hwang, S P et al. (1990) Estrogen-induced destabilization and associated degradation intermediates of apolipoprotein II mRNA. Prog Clin Biol Res 322:227-40
Fenjves, E S; Lee, J I; Garlick, J A et al. (1990) Prospects for epithelial gene therapy. Basic Life Sci 53:215-23
Binder, R; MacDonald, C C; Burch, J B et al. (1990) Expression of endogenous and transfected apolipoprotein II and vitellogenin II genes in an estrogen responsive chicken liver cell line. Mol Endocrinol 4:201-8

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