Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DK024031-18
Application #
2137665
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-12-01
Project End
1999-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Mayo Clinic, Rochester
Department
Type
DUNS #
City
Rochester
State
MN
Country
United States
Zip Code
55905
Munoz-Garrido, Patricia; Marin, José J G; Perugorria, María J et al. (2015) Ursodeoxycholic acid inhibits hepatic cystogenesis in experimental models of polycystic liver disease. J Hepatol 63:952-61
Masyuk, Anatoliy I; Masyuk, Tatyana V; Larusso, Nicholas F (2013) Exosomes in the pathogenesis, diagnostics and therapeutics of liver diseases. J Hepatol 59:621-5
Masyuk, Anatoliy I; Huang, Bing Q; Radtke, Brynn N et al. (2013) Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling. Am J Physiol Gastrointest Liver Physiol 304:G1013-24
Tietz Bogert, Pamela S; Huang, Bing Q; Gradilone, Sergio A et al. (2013) The zebrafish as a model to study polycystic liver disease. Zebrafish 10:211-7
Masyuk, Tatyana V; Radtke, Brynn N; Stroope, Angela J et al. (2013) Pasireotide is more effective than octreotide in reducing hepatorenal cystogenesis in rodents with polycystic kidney and liver diseases. Hepatology 58:409-21
O'Hara, Steven P; Tabibian, James H; Splinter, Patrick L et al. (2013) The dynamic biliary epithelia: molecules, pathways, and disease. J Hepatol 58:575-82
Banales, Jesús M; Sáez, Elena; Uriz, Miriam et al. (2012) Up-regulation of microRNA 506 leads to decreased Cl-/HCO3- anion exchanger 2 expression in biliary epithelium of patients with primary biliary cirrhosis. Hepatology 56:687-97
Masyuk, Tatyana V; Radtke, Brynn N; Stroope, Angela J et al. (2012) Inhibition of Cdc25A suppresses hepato-renal cystogenesis in rodent models of polycystic kidney and liver disease. Gastroenterology 142:622-633.e4
Larusso, Nicholas F (2011) Patients, cells, and organelles: the intersection of science and serendipity. Hepatology 53:1417-26
Huebert, Robert C; Jagavelu, Kumaravelu; Hendrickson, Helen I et al. (2011) Aquaporin-1 promotes angiogenesis, fibrosis, and portal hypertension through mechanisms dependent on osmotically sensitive microRNAs. Am J Pathol 179:1851-60

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