Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DK029808-17
Application #
2138240
Study Section
Special Emphasis Panel (NSS)
Project Start
1987-09-01
Project End
1999-03-31
Budget Start
1996-07-19
Budget End
1997-03-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Freeman, J L; Pitcher, J A; Li, X et al. (2000) alpha-Actinin is a potent regulator of G protein-coupled receptor kinase activity and substrate specificity in vitro. FEBS Lett 473:280-4
Michaely, P; Kamal, A; Anderson, R G et al. (1999) A requirement for ankyrin binding to clathrin during coated pit budding. J Biol Chem 274:35908-13
Zhang, X; Bennett, V (1998) Restriction of 480/270-kD ankyrin G to axon proximal segments requires multiple ankyrin G-specific domains. J Cell Biol 142:1571-81
Lambert, S; Davis, J Q; Bennett, V (1997) Morphogenesis of the node of Ranvier: co-clusters of ankyrin and ankyrin-binding integral proteins define early developmental intermediates. J Neurosci 17:7025-36
Kuhlman, P A; Hughes, C A; Bennett, V et al. (1996) A new function for adducin. Calcium/calmodulin-regulated capping of the barbed ends of actin filaments. J Biol Chem 271:7986-91
Schengrund, C L; DasGupta, B R; Hughes, C A et al. (1996) Ganglioside-induced adherence of botulinum and tetanus neurotoxins to adducin. J Neurochem 66:2556-61
Kordeli, E; Lambert, S; Bennett, V (1995) AnkyrinG. A new ankyrin gene with neural-specific isoforms localized at the axonal initial segment and node of Ranvier. J Biol Chem 270:2352-9
Hu, R J; Moorthy, S; Bennett, V (1995) Expression of functional domains of beta G-spectrin disrupts epithelial morphology in cultured cells. J Cell Biol 128:1069-80
Li, Z P; Burke, E P; Frank, J S et al. (1993) The cardiac Na+-Ca2+ exchanger binds to the cytoskeletal protein ankyrin. J Biol Chem 268:11489-91
Michaely, P; Bennett, V (1993) The membrane-binding domain of ankyrin contains four independently folded subdomains, each comprised of six ankyrin repeats. J Biol Chem 268:22703-9

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