Zinc and the Synthesis of Zinc Binding Proteins

Cousins, Robert J.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 5R37DK031127-15
• Application #: 2138578
• Study Section: Nutrition Study Section (NTN)
• Program Officer: May, Michael K
• Project Start: 1982-07-01
• Project End: 1997-06-30
• Budget Start: 1996-07-01
• Budget End: 1997-06-30
• Support Year: 15
• Fiscal Year: 1996

Institution

• Name: University of Florida
• Department: Nutrition
• Type: Schools of Earth Sciences/Natur
• DUNS #: 073130411
• City: Gainesville
• State: FL
• Country: United States
• Zip Code: 32611

Publications

Aydemir, Tolunay Beker; Chang, Shou-Mei; Guthrie, Gregory J et al. (2012) Zinc transporter ZIP14 functions in hepatic zinc, iron and glucose homeostasis during the innate immune response (endotoxemia). PLoS One 7:e48679

Ryu, Moon-Suhn; Guthrie, Gregory J; Maki, Alyssa B et al. (2012) Proteomic analysis shows the upregulation of erythrocyte dematin in zinc-restricted human subjects. Am J Clin Nutr 95:1096-102

Ryu, Moon-Suhn; Langkamp-Henken, Bobbi; Chang, Shou-Mei et al. (2011) Genomic analysis, cytokine expression, and microRNA profiling reveal biomarkers of human dietary zinc depletion and homeostasis. Proc Natl Acad Sci U S A 108:20970-5

Lichten, Louis A; Ryu, Moon-Suhn; Guo, Liang et al. (2011) MTF-1-mediated repression of the zinc transporter Zip10 is alleviated by zinc restriction. PLoS One 6:e21526

Guo, Liang; Lichten, Louis A; Ryu, Moon-Suhn et al. (2010) STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells. Proc Natl Acad Sci U S A 107:2818-23

Cousins, Robert J; Aydemir, Tolunay B; Lichten, Louis A (2010) Plenary Lecture 2: Transcription factors, regulatory elements and nutrient-gene communication. Proc Nutr Soc 69:91-4

Cousins, Robert J (2010) Gastrointestinal factors influencing zinc absorption and homeostasis. Int J Vitam Nutr Res 80:243-8

Liuzzi, Juan P; Guo, Liang; Chang, Shou-Mei et al. (2009) Krüppel-like factor 4 regulates adaptive expression of the zinc transporter Zip4 in mouse small intestine. Am J Physiol Gastrointest Liver Physiol 296:G517-23

Aydemir, Tolunay B; Liuzzi, Juan P; McClellan, Steve et al. (2009) Zinc transporter ZIP8 (SLC39A8) and zinc influence IFN-gamma expression in activated human T cells. J Leukoc Biol 86:337-48

Lichten, Louis A; Liuzzi, Juan P; Cousins, Robert J (2009) Interleukin-1beta contributes via nitric oxide to the upregulation and functional activity of the zinc transporter Zip14 (Slc39a14) in murine hepatocytes. Am J Physiol Gastrointest Liver Physiol 296:G860-7