Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DK032753-14
Application #
2138862
Study Section
Special Emphasis Panel (NSS)
Project Start
1983-07-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Physiology
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
de Lemos Barbosa, Carolina Monteiro; Souza-Menezes, Jackson; Amaral, Andressa Godoy et al. (2016) Regulation of CFTR Expression and Arginine Vasopressin Activity Are Dependent on Polycystin-1 in Kidney-Derived Cells. Cell Physiol Biochem 38:28-39
Peruchetti, Diogo B; Cheng, Jie; Caruso-Neves, Celso et al. (2014) Mis-regulation of mammalian target of rapamycin (mTOR) complexes induced by albuminuria in proximal tubules. J Biol Chem 289:16790-801
Santoso, Netty G; Cebotaru, Liudmila; Guggino, William B (2011) Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathway. Cell Physiol Biochem 27:715-26
Woodward, Owen M; Köttgen, Anna; Köttgen, Michael (2011) ABCG transporters and disease. FEBS J 278:3215-25
Tin, Adrienne; Woodward, Owen M; Kao, Wen Hong Linda et al. (2011) Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele. Hum Mol Genet 20:4056-68
Woodward, Owen M; Li, Yun; Yu, Shengqiang et al. (2010) Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1. PLoS One 5:e12305
Kwon, Young; Kim, Sang Hoon; Ronderos, David S et al. (2010) Drosophila TRPA1 channel is required to avoid the naturally occurring insect repellent citronellal. Curr Biol 20:1672-8
Guggino, Sandra E (2009) Can we generate new hypotheses about Dent's disease from gene analysis of a mouse model? Exp Physiol 94:191-6
Wright, Jerry; Morales, Marcelo M; Sousa-Menzes, Jackson et al. (2008) Transcriptional adaptation to Clcn5 knockout in proximal tubules of mouse kidney. Physiol Genomics 33:341-54
Guggino, Sandra E (2007) Mechanisms of disease: what can mouse models tell us about the molecular processes underlying Dent disease? Nat Clin Pract Nephrol 3:449-55

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