Membrane Pathology in Renal Cell Injury

Venkatachalam, Manjeri A.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 4R37DK037139-15
• Application #: 6400828
• Study Section: Special Emphasis Panel (NSS)
• Program Officer: Scherbenske, M James
• Project Start: 1987-07-01
• Project End: 2004-06-30
• Budget Start: 2001-07-01
• Budget End: 2002-06-30
• Support Year: 15
• Fiscal Year: 2001
• Total Cost: $517,446

Institution

• Name: University of Texas Health Science Center San Antonio
• Department: Pathology
• Type: Other Domestic Higher Education
• DUNS #: 800772162
• City: San Antonio
• State: TX
• Country: United States
• Zip Code: 78229

Publications

Venkatachalam, Manjeri A; Weinberg, Joel M (2017) Pericytes Preserve Capillary Integrity to Prevent Kidney Hypoxia. J Am Soc Nephrol 28:717-719

Singha, P K; Pandeswara, S; Venkatachalam, M A et al. (2013) Manumycin A inhibits triple-negative breast cancer growth through LC3-mediated cytoplasmic vacuolation death. Cell Death Dis 4:e457

Lan, Rongpei; Geng, Hui; Polichnowski, Aaron J et al. (2012) PTEN loss defines a TGF-?-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis. Am J Physiol Renal Physiol 302:F1210-23

Geng, Hui; Lan, Rongpei; Singha, Prajjal K et al. (2012) Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and G?q-mediated Rho and ?v?6 integrin-dependent activation of TGF-?. Am J Pathol 181:1236-49

Venkatachalam, Manjeri A; Griffin, Karen A; Lan, Rongpei et al. (2010) Acute kidney injury: a springboard for progression in chronic kidney disease. Am J Physiol Renal Physiol 298:F1078-94

Kar, Rekha; Mishra, Nandita; Singha, Prajjal K et al. (2010) Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1. Biochem Biophys Res Commun 399:548-54

Zitta, Karina; Brandt, Berenice; Wuensch, Annegret et al. (2010) Interleukin-1beta regulates cell proliferation and activity of extracellular matrix remodelling enzymes in cultured primary pig heart cells. Biochem Biophys Res Commun 399:542-7

Singha, Prajjal K; Yeh, I-Tien; Venkatachalam, Manjeri A et al. (2010) Transforming growth factor-beta (TGF-beta)-inducible gene TMEPAI converts TGF-beta from a tumor suppressor to a tumor promoter in breast cancer. Cancer Res 70:6377-83

Mishra, Nandita; Kar, Rekha; Singha, Prajjal K et al. (2010) Inhibition of mitochondrial division through covalent modification of Drp1 protein by 15 deoxy-Delta(12,14)-prostaglandin J2. Biochem Biophys Res Commun 395:17-24

Lan, Rongpei; Geng, Hui; Hwang, Yoon et al. (2010) A novel wounding device suitable for quantitative biochemical analysis of wound healing and regeneration of cultured epithelium. Wound Repair Regen 18:159-67