Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37DK038311-13
Application #
3483718
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1977-02-01
Project End
1995-08-30
Budget Start
1990-09-01
Budget End
1991-08-31
Support Year
13
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Yale University
Department
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Yono, Makoto; Yamamoto, Yasuhiro; Imanishi, Aya et al. (2008) Differential effects of prazosin and naftopidil on pelvic blood flow and nitric oxide synthase levels in spontaneously hypertensive rats. J Recept Signal Transduct Res 28:403-12
Yono, Makoto; Mane, Shrikant M; Lin, Aiping et al. (2008) Differential effects of diabetes induced by streptozotocin and that develops spontaneously on prostate growth in Bio Breeding (BB) rats. Life Sci 83:192-7
Yono, Makoto; Foster Jr, Harris E; Weiss, Robert M et al. (2006) Age related changes in the functional, biochemical and molecular properties of alpha1-adrenoceptors in the rat genitourinary tract. J Urol 176:1214-9
Wheeler, Marcia A; Ayyagari, Rajasekhara R; Wheeler, George L et al. (2005) Regulation of cyclic nucleotides in the urinary tract. J Smooth Muscle Res 41:1-21
Yono, Makoto; Pouresmail, Mehdi; Takahashi, Wataru et al. (2005) Effect of insulin treatment on tissue size of the genitourinary tract in BB rats with spontaneously developed and streptozotocin-induced diabetes. Naunyn Schmiedebergs Arch Pharmacol 372:251-5
Yono, Makoto; Foster Jr, Harris E; Shin, David et al. (2005) Molecular classification of doxazosin-induced alterations in the rat prostate using gene expression profiling. Life Sci 77:470-9
Yono, Makoto; Latifpour, Jamshid; Takahashi, Wataru et al. (2004) Age-related changes in the properties of the endothelin receptor system at protein and mRNA levels in the rat vas deferens. J Recept Signal Transduct Res 24:53-66
Foster Jr, Harris E; Yono, Makoto; Shin, David et al. (2004) Effects of chronic administration of doxazosin on alpha1-adrenoceptors in the rat prostate. J Urol 172:2465-70
Kang, Walter S; Tamarkin, Frank J; Wheeler, Marcia A et al. (2004) Rapid up-regulation of endothelial nitric-oxide synthase in a mouse model of Escherichia coli lipopolysaccharide-induced bladder inflammation. J Pharmacol Exp Ther 310:452-8
Yono, Makoto; Foster Jr, Harris E; Shin, David et al. (2004) Doxazosin-induced up-regulation of alpha 1A-adrenoceptor mRNA in the rat lower urinary tract. Can J Physiol Pharmacol 82:872-8

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