Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37DK039298-09
Application #
2140883
Study Section
General Medicine B Study Section (GMB)
Project Start
1987-07-01
Project End
2001-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Dallas
State
TX
Country
United States
Zip Code
75390
Zacchia, Miriam; Tian, Xuefei; Zona, Enrica et al. (2018) Acid Stimulation of the Citrate Transporter NaDC-1 Requires Pyk2 and ERK1/2 Signaling Pathways. J Am Soc Nephrol 29:1720-1730
Liu, Liping; Zacchia, Miriam; Tian, Xuefei et al. (2010) Acid regulation of NaDC-1 requires a functional endothelin B receptor. Kidney Int 78:895-904
Zacchia, Miriam; Preisig, Patricia (2010) Low urinary citrate: an overview. J Nephrol 23 Suppl 16:S49-56
Yang, Xiaojing; Huang, Hai-Chang; Yin, Helen et al. (2007) RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3. Am J Physiol Renal Physiol 293:F1054-64
Laghmani, Kamel; Sakamoto, Aiji; Yanagisawa, Masashi et al. (2005) A consensus sequence in the endothelin-B receptor second intracellular loop is required for NHE3 activation by endothelin-1. Am J Physiol Renal Physiol 288:F732-9
Li, Shaoying; Sato, Soichiro; Yang, Xiaojing et al. (2004) Pyk2 activation is integral to acid stimulation of sodium/hydrogen exchanger 3. J Clin Invest 114:1782-9
Licht, Christoph; Laghmani, Kamel; Yanagisawa, Masashi et al. (2004) An autocrine role for endothelin-1 in the regulation of proximal tubule NHE3. Kidney Int 65:1320-6
Aruga, Seiji; Pajor, Ana M; Nakamura, Kiyoshi et al. (2004) OKP cells express the Na-dicarboxylate cotransporter NaDC-1. Am J Physiol Cell Physiol 287:C64-72
Alpern, Robert J; Preisig, Patricia A (2004) Dietary acid, endothelins, and sleep. Trans Am Clin Climatol Assoc 115:385-93; discussion 393-4
Capasso, Giovambattista; Rizzo, Maria; Pica, Angelo et al. (2002) Bicarbonate reabsorption and NHE-3 expression: abundance and activity are increased in Henle's loop of remnant rats. Kidney Int 62:2126-35

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