Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK047556-12
Application #
7019168
Study Section
Special Emphasis Panel (NSS)
Program Officer
Mullins, Christopher V
Project Start
1994-08-01
Project End
2009-11-30
Budget Start
2005-12-01
Budget End
2006-11-30
Support Year
12
Fiscal Year
2006
Total Cost
$357,731
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Minciacchi, Valentina R; You, Sungyong; Spinelli, Cristiana et al. (2015) Large oncosomes contain distinct protein cargo and represent a separate functional class of tumor-derived extracellular vesicles. Oncotarget 6:11327-41
Yang, Wei; Kim, Yongsoo; Kim, Taek-Kyun et al. (2012) Integration analysis of quantitative proteomics and transcriptomics data identifies potential targets of frizzled-8 protein-related antiproliferative factor in vivo. BJU Int 110:E1138-46
Kim, Jayoung; Keay, Susan K; You, Sungyong et al. (2012) A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2. PLoS One 7:e50392
Kim, Jayoung; Ji, Mihee; DiDonato, Joseph A et al. (2011) An hTERT-immortalized human urothelial cell line that responds to anti-proliferative factor. In Vitro Cell Dev Biol Anim 47:2-9
Yang, Wei; Chung, Yeun Goo; Kim, Yongsoo et al. (2011) Quantitative proteomics identifies a beta-catenin network as an element of the signaling response to Frizzled-8 protein-related antiproliferative factor. Mol Cell Proteomics 10:M110.007492
Pelton, Kristine; Di Vizio, Dolores; Insabato, Luigi et al. (2010) Ezetimibe reduces enlarged prostate in an animal model of benign prostatic hyperplasia. J Urol 184:1555-9
Yang, Wei; Di Vizio, Dolores; Kirchner, Marc et al. (2010) Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes. Mol Cell Proteomics 9:54-70
Kim, Jayoung; Yanagihara, Yutaka; Kikugawa, Tadahiko et al. (2009) A signaling network in phenylephrine-induced benign prostatic hyperplasia. Endocrinology 150:3576-83
Kim, Jayoung; Keay, Susan K; Freeman, Michael R (2009) Heparin-binding epidermal growth factor-like growth factor functionally antagonizes interstitial cystitis antiproliferative factor via mitogen-activated protein kinase pathway activation. BJU Int 103:541-6
Solomon, Keith R; Pelton, Kristine; Boucher, Kelly et al. (2009) Ezetimibe is an inhibitor of tumor angiogenesis. Am J Pathol 174:1017-26

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