Protein degradation and cholesterol regulation

Agency: National Institute of Health (NIH)
Institute: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type: Method to Extend Research in Time (MERIT) Award (R37)
Project #: 4R37DK051996-21
Application #: 9376975
Study Section: Special Emphasis Panel (NSS)
Program Officer: Haft, Carol R


NIH 2020 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California, San Diego
NIH 2019 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California, San Diego
NIH 2018 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California, San Diego
NIH 2017 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California San Diego	$401,158
NIH 2016 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California San Diego
NIH 2015 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California San Diego	$324,869
NIH 2014 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California San Diego	$327,774
NIH 2013 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California San Diego	$317,122
NIH 2012 R37 DK	Protein degradation and cholesterol regulation Hampton, Randolph Y. / University of California San Diego	$328,973

Wangeline, Margaret A; Hampton, Randolph Y (2018) ""Mallostery""-ligand-dependent protein misfolding enables physiological regulation by ERAD. J Biol Chem 293:14937-14950

Neal, Sonya; Jaeger, Philipp A; Duttke, Sascha H et al. (2018) The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Mol Cell 69:306-320.e4

Jaeger, Philipp A; Ornelas, Lilia; McElfresh, Cameron et al. (2018) Systematic Gene-to-Phenotype Arrays: A High-Throughput Technique for Molecular Phenotyping. Mol Cell 69:321-333.e3

Wangeline, Margaret A; Vashistha, Nidhi; Hampton, Randolph Y (2017) Proteostatic Tactics in the Strategy of Sterol Regulation. Annu Rev Cell Dev Biol 33:467-489

Vashistha, Nidhi; Neal, Sonya E; Singh, Amanjot et al. (2016) Direct and essential function for Hrd3 in ER-associated degradation. Proc Natl Acad Sci U S A 113:5934-9

Hampton, Randolph Y; Sommer, Thomas (2012) Finding the will and the way of ERAD substrate retrotranslocation. Curr Opin Cell Biol 24:460-6

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