Agency
National Institute of Health (NIH)
Institute
National Institute of Environmental Health Sciences (NIEHS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37ES001978-18
Application #
2153091
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-07-01
Project End
1997-06-30
Budget Start
1995-07-01
Budget End
1997-06-30
Support Year
18
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Oregon State University
Department
Biochemistry
Type
Schools of Arts and Sciences
DUNS #
053599908
City
Corvallis
State
OR
Country
United States
Zip Code
97339
Vassallo, Jeffrey D; Kaetzel, Rhonda S; Born, Stephanie L et al. (2010) Gamma-glutamyl transpeptidase null mice fail to develop tolerance to coumarin-induced Clara cell toxicity. Food Chem Toxicol 48:1612-8
Will, Yvonne; Kaetzel, Rhonda S; Brown, Marda K et al. (2002) In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knocko Arch Biochem Biophys 397:399-406
Lawrence, B P; Will, Y; Reed, D J et al. (2000) Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses. Eur J Immunol 30:1902-10
Will, Y; Fischer, K A; Horton, R A et al. (2000) gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function. Hepatology 32:740-9
Mustacich, D J; Shields, J; Horton, R A et al. (1998) Biliary secretion of alpha-tocopherol and the role of the mdr2 P-glycoprotein in rats and mice. Arch Biochem Biophys 350:183-92
Mustacich, D J; Brown, M K; Reed, D J (1996) Colchicine and vinblastine prevent the piperonyl butoxide-induced increase in rat biliary output of alpha-tocopherol. Toxicol Appl Pharmacol 139:411-7
Gardiner, C S; Reed, D J (1995) Glutathione redox cycle-driven recovery of reduced glutathione after oxidation by tertiary-butyl hydroperoxide in preimplantation mouse embryos. Arch Biochem Biophys 321:6-12
Reed, D J (1995) Cystathionine. Methods Enzymol 252:92-102
Reed, D J; Savage, M K (1995) Influence of metabolic inhibitors on mitochondrial permeability transition and glutathione status. Biochim Biophys Acta 1271:43-50
Gardiner, C S; Reed, D J (1995) Synthesis of glutathione in the preimplantation mouse embryo. Arch Biochem Biophys 318:30-6

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