Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37EY008879-06
Application #
2162533
Study Section
Special Emphasis Panel (NSS)
Project Start
1996-01-19
Project End
1997-12-31
Budget Start
1996-01-19
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Ophthalmology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Crook, R B; Takahashi, K; Mead, A et al. (2000) The role of NaKCl cotransport in blood-to-aqueous chloride fluxes across rabbit ciliary epithelium. Invest Ophthalmol Vis Sci 41:2574-83
Hirata, K; Nathanson, M H; Burgstahler, A D et al. (1999) Relationship between inositol 1,4,5-trisphosphate receptor isoforms and subcellular Ca2+ signaling patterns in nonpigmented ciliary epithelia. Invest Ophthalmol Vis Sci 40:2046-53
Sears, J; Nakano, T; Sears, M (1998) Adrenergic-mediated connexin43 phosphorylation in the ocular ciliary epithelium. Curr Eye Res 17:104-7
Hirata, K; Nathanson, M H; Sears, M L (1998) Novel paracrine signaling mechanism in the ocular ciliary epithelium. Proc Natl Acad Sci U S A 95:8381-6
Chen, S; Wan, X L; Sears, M (1998) pICln can regulate swelling-induced Cl- currents in either layer of rabbit ciliary epithelium. Biochem Biophys Res Commun 246:59-63
Wan, X L; Chen, S; Sears, M (1997) Cloning and functional expression of a swelling-induced chloride conductance regulatory protein, plCln, from rabbit ocular ciliary epithelium. Biochem Biophys Res Commun 239:692-6
Chen, S; Sears, M (1997) A low conductance chloride channel in the basolateral membranes of the non-pigmented ciliary epithelium of the rabbit eye. Curr Eye Res 16:710-8
Wan, X L; Sears, J; Chen, S et al. (1997) Circadian aqueous flow mediated by beta-arrestin induced homologous desensitization. Exp Eye Res 64:1005-11
Suzuki, Y; Nakano, T; Sears, M (1997) Calcium signals from intact rabbit ciliary epithelium observed with confocal microscopy. Curr Eye Res 16:166-75
Horio, B; Sears, M; Mead, A et al. (1996) Regulation and bioelectrical effects of cyclic adenosine monophosphate production in the ciliary epithelial bilayer. Invest Ophthalmol Vis Sci 37:607-12

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