Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM012592-32
Application #
2168586
Study Section
Molecular and Cellular Biophysics Study Section (BBCA)
Project Start
1977-02-01
Project End
1997-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
32
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Chuntonov, Lev; Pazos, Ileana M; Ma, Jianqiang et al. (2015) Kinetics of exchange between zero-, one-, and two-hydrogen-bonded states of methyl and ethyl acetate in methanol. J Phys Chem B 119:4512-20
Ghosh, Ayanjeet; Tucker, Matthew J; Gai, Feng (2014) 2D IR spectroscopy of histidine: probing side-chain structure and dynamics via backbone amide vibrations. J Phys Chem B 118:7799-805
Ma, Jianqiang; Pazos, Ileana M; Gai, Feng (2014) Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO). Proc Natl Acad Sci U S A 111:8476-81
Ghosh, Ayanjeet; Wang, Jun; Moroz, Yurii S et al. (2014) 2D IR spectroscopy reveals the role of water in the binding of channel-blocking drugs to the influenza M2 channel. J Chem Phys 140:235105
Pazos, Ileana M; Ghosh, Ayanjeet; Tucker, Matthew J et al. (2014) Ester carbonyl vibration as a sensitive probe of protein local electric field. Angew Chem Int Ed Engl 53:6080-4
Ma, Jianqiang; Komatsu, Hiroaki; Kim, Yung Sam et al. (2013) Intrinsic structural heterogeneity and long-term maturation of amyloid ? peptide fibrils. ACS Chem Neurosci 4:1236-43
Singh, Prabhat K; Kuroda, Daniel G; Hochstrasser, Robin M (2013) An ion's perspective on the molecular motions of nanoconfined water: a two-dimensional infrared spectroscopy study. J Phys Chem B 117:9775-84
Kuroda, Daniel G; Abdo, Mohannad; Chuntonov, Lev et al. (2013) Vibrational dynamics of a non-degenerate ultrafast rotor: the (C12,C13)-oxalate ion. J Chem Phys 139:164514
Kuroda, Daniel G; Bauman, Joseph D; Challa, J Reddy et al. (2013) Snapshot of the equilibrium dynamics of a drug bound to HIV-1 reverse transcriptase. Nat Chem 5:174-81
Chuntonov, Lev; Kuroda, Daniel G; Ghosh, Ayanjeet et al. (2013) Quantum Beats and Coherence Decay in Degenerate States Split by Solvation. J Phys Chem Lett 4:1866-1871

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