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Prorok, M; Albeck, A; Foxman, B M et al. (1994) Chloroketone hydrolysis by chymotrypsin and N-methylhistidyl-57-chymotrypsin: implications for the mechanism of chymotrypsin inactivation by chloroketones. Biochemistry 33:9784-90
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Wray, J W; Abeles, R H (1993) A bacterial enzyme that catalyzes formation of carbon monoxide. J Biol Chem 268:21466-9
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Parisi, M F; Abeles, R H (1992) Inhibition of chymotrypsin by fluorinated alpha-keto acid derivatives. Biochemistry 31:9429-35
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Epstein, D M; Abeles, R H (1992) Role of serine 214 and tyrosine 171, components of the S2 subsite of alpha-lytic protease, in catalysis. Biochemistry 31:11216-23
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Hu, L Y; Abeles, R H (1990) Inhibition of cathepsin B and papain by peptidyl alpha-keto esters, alpha-keto amides, alpha-diketones, and alpha-keto acids. Arch Biochem Biophys 281:271-4
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Brady, K; Wei, A Z; Ringe, D et al. (1990) Structure of chymotrypsin-trifluoromethyl ketone inhibitor complexes: comparison of slowly and rapidly equilibrating inhibitors. Biochemistry 29:7600-7
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Brady, K; Abeles, R H (1990) Inhibition of chymotrypsin by peptidyl trifluoromethyl ketones: determinants of slow-binding kinetics. Biochemistry 29:7608-17
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Govardhan, C P; Abeles, R H (1990) Structure-activity studies of fluoroketone inhibitors of alpha-lytic protease and human leukocyte elastase. Arch Biochem Biophys 280:137-46
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Abeles, R H; Alston, T A (1990) Enzyme inhibition by fluoro compounds. J Biol Chem 265:16705-8
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Allen, K N; Abeles, R H (1989) Inhibition kinetics of acetylcholinesterase with fluoromethyl ketones. Biochemistry 28:8466-73
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