Synthesis and Assembly of Flagellar Proteins

Rosenbaum, Joel L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Institute of General Medical Sciences (NIGMS)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 4R37GM014642-37
• Application #: 6611656
• Study Section: Special Emphasis Panel (NSS)
• Program Officer: Deatherage, James F
• Project Start: 1975-09-01
• Project End: 2009-01-31
• Budget Start: 2004-02-01
• Budget End: 2005-01-31
• Support Year: 37
• Fiscal Year: 2004
• Total Cost: $812,215

Institution

• Name: Yale University
• Department: Physiology
• Type: Schools of Arts and Sciences
• DUNS #: 043207562
• City: New Haven
• State: CT
• Country: United States
• Zip Code: 06520

Publications

Long, Huan; Zhang, Fan; Xu, Nannan et al. (2016) Comparative Analysis of Ciliary Membranes and Ectosomes. Curr Biol 26:3327-3335

Diener, Dennis R; Lupetti, Pietro; Rosenbaum, Joel L (2015) Proteomic analysis of isolated ciliary transition zones reveals the presence of ESCRT proteins. Curr Biol 25:379-384

Wood, Christopher R; Rosenbaum, Joel L (2014) Proteins of the ciliary axoneme are found on cytoplasmic membrane vesicles during growth of cilia. Curr Biol 24:1114-20

Wood, Christopher R; Huang, Kaiyao; Diener, Dennis R et al. (2013) The cilium secretes bioactive ectosomes. Curr Biol 23:906-11

Mencarelli, Caterina; Mitchell, Aaron; Leoncini, Roberto et al. (2013) Isolation of intraflagellar transport trains. Cytoskeleton (Hoboken) 70:439-52

Satish Tammana, Trinadh V; Tammana, Damayanti; Diener, Dennis R et al. (2013) Centrosomal protein CEP104 (Chlamydomonas FAP256) moves to the ciliary tip during ciliary assembly. J Cell Sci 126:5018-29

Yuan, Shiaulou; Zhao, Lu; Sun, Zhaoxia (2013) Dissecting the functional interplay between the TOR pathway and the cilium in zebrafish. Methods Enzymol 525:159-89

Gupta, Anjali; Diener, Dennis R; Sivadas, Priyanka et al. (2012) The versatile molecular complex component LC8 promotes several distinct steps of flagellar assembly. J Cell Biol 198:115-26

Yuan, Shiaulou; Li, Jade; Diener, Dennis R et al. (2012) Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation. Proc Natl Acad Sci U S A 109:2021-6

Kohno, Takahiro; Wakabayashi, Ken-ichi; Diener, Dennis R et al. (2011) Subunit interactions within the Chlamydomonas flagellar spokehead. Cytoskeleton (Hoboken) 68:237-46