Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM017151-35
Application #
6760958
Study Section
Special Emphasis Panel (NSS)
Program Officer
Rhoades, Marcus M
Project Start
1978-06-01
Project End
2007-06-30
Budget Start
2004-07-01
Budget End
2005-06-30
Support Year
35
Fiscal Year
2004
Total Cost
$524,927
Indirect Cost

  Institution

Name
Massachusetts Institute of Technology
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
001425594
City
Cambridge
State
MA
Country
United States
Zip Code
02139

  Publications

Arguello, Tania; Köhrer, Caroline; RajBhandary, Uttam L et al. (2018) Mitochondrial methionyl N-formylation affects steady-state levels of oxidative phosphorylation complexes and their organization into supercomplexes. J Biol Chem 293:15021-15032
Ghosal, Anubrata; Köhrer, Caroline; Babu, Vignesh M P et al. (2017) C21orf57 is a human homologue of bacterial YbeY proteins. Biochem Biophys Res Commun 484:612-617
Vercruysse, Maarten; Köhrer, Caroline; Shen, Yang et al. (2016) Identification of YbeY-Protein Interactions Involved in 16S rRNA Maturation and Stress Regulation in Escherichia coli. MBio 7:
Niehues, Sven; Bussmann, Julia; Steffes, Georg et al. (2015) Impaired protein translation in Drosophila models for Charcot-Marie-Tooth neuropathy caused by mutant tRNA synthetases. Nat Commun 6:7520
Bhattacharya, Arpita; Köhrer, Caroline; Mandal, Debabrata et al. (2015) Nonsense suppression in archaea. Proc Natl Acad Sci U S A 112:6015-20
Mandal, Debabrata; Köhrer, Caroline; Su, Dan et al. (2014) Identification and codon reading properties of 5-cyanomethyl uridine, a new modified nucleoside found in the anticodon wobble position of mutant haloarchaeal isoleucine tRNAs. RNA 20:177-88
Sinha, Akesh; Köhrer, Caroline; Weber, Michael H W et al. (2014) Biochemical characterization of pathogenic mutations in human mitochondrial methionyl-tRNA formyltransferase. J Biol Chem 289:32729-41
Vercruysse, Maarten; Köhrer, Caroline; Davies, Bryan W et al. (2014) The highly conserved bacterial RNase YbeY is essential in Vibrio cholerae, playing a critical role in virulence, stress regulation, and RNA processing. PLoS Pathog 10:e1004175
Köhrer, Caroline; Mandal, Debabrata; Gaston, Kirk W et al. (2014) Life without tRNAIle-lysidine synthetase: translation of the isoleucine codon AUA in Bacillus subtilis lacking the canonical tRNA2Ile. Nucleic Acids Res 42:1904-15
Jacob, Asha Ivy; Kohrer, Caroline; Davies, Bryan William et al. (2013) Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation. Mol Cell 49:427-38

Showing the most recent 10 out of 36 publications