Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM022525-31
Application #
7050182
Study Section
Special Emphasis Panel (NSS)
Program Officer
Poodry, Clifton A
Project Start
1979-05-01
Project End
2008-04-30
Budget Start
2006-05-01
Budget End
2007-04-30
Support Year
31
Fiscal Year
2006
Total Cost
$408,635
Indirect Cost
Name
University of Texas Sw Medical Center Dallas
Department
Biochemistry
Type
Schools of Medicine
DUNS #
800771545
City
Dallas
State
TX
Country
United States
Zip Code
75390
Kucej, Martin; Kucejova, Blanka; Subramanian, Ramiah et al. (2008) Mitochondrial nucleoids undergo remodeling in response to metabolic cues. J Cell Sci 121:1861-8
Liu, Zhengchang; Thornton, Janet; Spirek, Mario et al. (2008) Activation of the SPS amino acid-sensing pathway in Saccharomyces cerevisiae correlates with the phosphorylation state of a sensor component, Ptr3. Mol Cell Biol 28:551-63
Kucej, Martin; Butow, Ronald A (2007) Evolutionary tinkering with mitochondrial nucleoids. Trends Cell Biol 17:586-92
Liu, Zhengchang; Butow, Ronald A (2006) Mitochondrial retrograde signaling. Annu Rev Genet 40:159-85
Giannattasio, Sergio; Liu, Zhengchang; Thornton, Janet et al. (2005) Retrograde response to mitochondrial dysfunction is separable from TOR1/2 regulation of retrograde gene expression. J Biol Chem 280:42528-35
Chen, Xin Jie; Wang, Xiaowen; Kaufman, Brett A et al. (2005) Aconitase couples metabolic regulation to mitochondrial DNA maintenance. Science 307:714-7
Ferreira Junior, Jose Ribamar; Spirek, Mario; Liu, Zhengchang et al. (2005) Interaction between Rtg2p and Mks1p in the regulation of the RTG pathway of Saccharomyces cerevisiae. Gene 354:2-8
Liu, Zhengchang; Spirek, Mario; Thornton, Janet et al. (2005) A novel degron-mediated degradation of the RTG pathway regulator, Mks1p, by SCFGrr1. Mol Biol Cell 16:4893-904
Butow, Ronald A; Avadhani, Narayan G (2004) Mitochondrial signaling: the retrograde response. Mol Cell 14:1-15
Liu, Zhengchang; Sekito, Takayuki; Spirek, Mario et al. (2003) Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. Mol Cell 12:401-11

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