Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM022846-22
Application #
2173994
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Johns Hopkins University
Department
Biochemistry
Type
Schools of Public Health
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218

  Publications

Baccarelli, A; Calista, D; Minghetti, P et al. (2004) XPD gene polymorphism and host characteristics in the association with cutaneous malignant melanoma risk. Br J Cancer 90:497-502
Qiao, Yawei; Spitz, Margaret R; Shen, Hongbing et al. (2002) Modulation of repair of ultraviolet damage in the host-cell reactivation assay by polymorphic XPC and XPD/ERCC2 genotypes. Carcinogenesis 23:295-9
Qiao, Yawei; Spitz, Margaret R; Guo, Zhaozheng et al. (2002) Rapid assessment of repair of ultraviolet DNA damage with a modified host-cell reactivation assay using a luciferase reporter gene and correlation with polymorphisms of DNA repair genes in normal human lymphocytes. Mutat Res 509:165-74
Landi, Maria Teresa; Baccarelli, Andrea; Tarone, Robert E et al. (2002) DNA repair, dysplastic nevi, and sunlight sensitivity in the development of cutaneous malignant melanoma. J Natl Cancer Inst 94:94-101
Grossman, L (2001) Nucleotide excision repair: Dick Setlow: how he influenced my scientific life. Environ Mol Mutagen 38:144-52
Hildebrand, E L; Grossman, L (1999) Oligomerization of the UvrB nucleotide excision repair protein of Escherichia coli. J Biol Chem 274:27885-90
Kovalsky, O I; Lin, C G; Grossman, L (1998) Selection of monoclonal antibodies for probing of functional intermediates in incision of UV-irradiated DNA by Uvr(A)BC endonuclease from Escherichia coli. Biochim Biophys Acta 1397:91-101
Kovalsky, O I; Grossman, L (1998) Accessibility of epitopes on UvrB protein in intermediates generated during incision of UV-irradiated DNA by the Escherichia coli Uvr(A)BC endonuclease. J Biol Chem 273:21009-14
Hildebrand, E L; Grossman, L (1998) Introduction of a tryptophan reporter group into the ATP binding motif of the Escherichia coli UvrB protein for the study of nucleotide binding and conformational dynamics. J Biol Chem 273:7818-27
ClGL; Kovalsky, O; Grossman, L (1998) Transcription coupled nucleotide excision repair by isolated Escherichia coli membrane-associated nucleoids. Nucleic Acids Res 26:1466-72

Showing the most recent 10 out of 36 publications