Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM023105-21
Application #
2174041
Study Section
Physical Biochemistry Study Section (PB)
Project Start
1976-05-01
Project End
1999-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
21
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Wisconsin Madison
Department
Biochemistry
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715

  Publications

Fillingame, Robert H; Steed, P Ryan (2014) Half channels mediating H(+) transport and the mechanism of gating in the Fo sector of Escherichia coli F1Fo ATP synthase. Biochim Biophys Acta 1837:1063-8
Steed, P Ryan; Kraft, Kaitlin A; Fillingame, Robert H (2014) Interacting cytoplasmic loops of subunits a and c of Escherichia coli F1F0 ATP synthase gate H+ transport to the cytoplasm. Proc Natl Acad Sci U S A 111:16730-5
Steed, P Ryan; Fillingame, Robert H (2014) Residues in the polar loop of subunit c in Escherichia coli ATP synthase function in gating proton transport to the cytoplasm. J Biol Chem 289:2127-38
Moore, Kyle J; Fillingame, Robert H (2013) Obstruction of transmembrane helical movements in subunit a blocks proton pumping by F1Fo ATP synthase. J Biol Chem 288:25535-41
DeLeon-Rangel, Jessica; Ishmukhametov, Robert R; Jiang, Warren et al. (2013) Interactions between subunits a and b in the rotary ATP synthase as determined by cross-linking. FEBS Lett 587:892-7
Uhlemann, Eva-Maria E; Pierson, Hannah E; Fillingame, Robert H et al. (2012) Cell-free synthesis of membrane subunits of ATP synthase in phospholipid bicelles: NMR shows subunit a fold similar to the protein in the cell membrane. Protein Sci 21:279-88
Dong, Hui; Fillingame, Robert H (2010) Chemical reactivities of cysteine substitutions in subunit a of ATP synthase define residues gating H+ transport from each side of the membrane. J Biol Chem 285:39811-8
Steed, P Ryan; Fillingame, Robert H (2009) Aqueous accessibility to the transmembrane regions of subunit c of the Escherichia coli F1F0 ATP synthase. J Biol Chem 284:23243-50
Moore, Kyle J; Angevine, Christine M; Vincent, Owen D et al. (2008) The cytoplasmic loops of subunit a of Escherichia coli ATP synthase may participate in the proton translocating mechanism. J Biol Chem 283:13044-52
Moore, Kyle J; Fillingame, Robert H (2008) Structural interactions between transmembrane helices 4 and 5 of subunit a and the subunit c ring of Escherichia coli ATP synthase. J Biol Chem 283:31726-35

Showing the most recent 10 out of 70 publications