Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM023547-28
Application #
6783297
Study Section
Special Emphasis Panel (NSS)
Program Officer
Marino, Pamela
Project Start
1977-02-01
Project End
2006-07-31
Budget Start
2004-08-01
Budget End
2005-07-31
Support Year
28
Fiscal Year
2004
Total Cost
$399,926
Indirect Cost
Name
University of California San Francisco
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
094878337
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Patnode, Michael L; Bando, Jennifer K; Krummel, Matthew F et al. (2014) Leukotriene B4 amplifies eosinophil accumulation in response to nematodes. J Exp Med 211:1281-8
Patnode, Michael L; Cheng, Chu-Wen; Chou, Chi-Chi et al. (2013) Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue. J Biol Chem 288:26533-45
Patnode, Michael L; Yu, Shin-Yi; Cheng, Chu-Wen et al. (2013) KSGal6ST generates galactose-6-O-sulfate in high endothelial venules but does not contribute to L-selectin-dependent lymphocyte homing. Glycobiology 23:381-94
Uchimura, Kenji; Morimoto-Tomita, Megumi; Bistrup, Annette et al. (2006) HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1. BMC Biochem 7:2
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Uchimura, Kenji; Gauguet, Jean-Marc; Singer, Mark S et al. (2005) A major class of L-selectin ligands is eliminated in mice deficient in two sulfotransferases expressed in high endothelial venules. Nat Immunol 6:1105-13
Pablos, Jose L; Santiago, Begona; Tsay, Durwin et al. (2005) A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells. BMC Immunol 6:6
Gauguet, Jean-Marc; Rosen, Steven D; Marth, Jamey D et al. (2004) Core 2 branching beta1,6-N-acetylglucosaminyltransferase and high endothelial cell N-acetylglucosamine-6-sulfotransferase exert differential control over B- and T-lymphocyte homing to peripheral lymph nodes. Blood 104:4104-12
Uchimura, Kenji; Kadomatsu, Kenji; El-Fasakhany, Fathy M et al. (2004) N-acetylglucosamine 6-O-sulfotransferase-1 regulates expression of L-selectin ligands and lymphocyte homing. J Biol Chem 279:35001-8

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