Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM023573-19
Application #
2174128
Study Section
Special Emphasis Panel (NSS)
Project Start
1977-09-09
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Biochemistry
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Pool, C T; Thompson, T E (1999) Methods for dual, site-specific derivatization of bovine pancreatic trypsin inhibitor: trypsin protection of lysine-15 and attachment of fatty acids or hydrophobic peptides at the N-terminus. Bioconjug Chem 10:221-30
Sugar, I P; Thompson, T E; Biltonen, R L (1999) Monte Carlo simulation of two-component bilayers: DMPC/DSPC mixtures. Biophys J 76:2099-110
Pool, C T; Thompson, T E (1998) Chain length and temperature dependence of the reversible association of model acylated proteins with lipid bilayers. Biochemistry 37:10246-55
Piknova, B; Marsh, D; Thompson, T E (1997) Fluorescence quenching and electron spin resonance study of percolation in a two-phase lipid bilayer containing bacteriorhodopsin. Biophys J 72:2660-8
Bar, L K; Barenholz, Y; Thompson, T E (1997) Effect of sphingomyelin composition on the phase structure of phosphatidylcholine-sphingomyelin bilayers. Biochemistry 36:2507-16
Schram, V; Thompson, T E (1997) Influence of the intrinsic membrane protein bacteriorhodopsin on gel-phase domain topology in two-component phase-separated bilayers. Biophys J 72:2217-25
Palestini, P; Allietta, M; Sonnino, S et al. (1995) Gel phase preference of ganglioside GM1 at low concentration in two-component, two-phase phosphatidylcholine bilayers depends upon the ceramide moiety. Biochim Biophys Acta 1235:221-30
Sankaram, M B; Marsh, D; Gierasch, L M et al. (1994) Reorganization of lipid domain structure in membranes by a transmembrane peptide: an ESR spin label study on the effect of the Escherichia coli outer membrane protein A signal peptide on the fluid lipid domain connectivity in binary mixtures of dimyristoy Biophys J 66:1959-68
Almeida, P F; Vaz, W L; Thompson, T E (1993) Percolation and diffusion in three-component lipid bilayers: effect of cholesterol on an equimolar mixture of two phosphatidylcholines. Biophys J 64:399-412
Almeida, P F; Vaz, W L; Thompson, T E (1992) Lateral diffusion and percolation in two-phase, two-component lipid bilayers. Topology of the solid-phase domains in-plane and across the lipid bilayer. Biochemistry 31:7198-210

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