Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37GM024663-19
Application #
2174301
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-01-01
Project End
2000-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
19
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts Institute of Technology
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
City
Cambridge
State
MA
Country
United States
Zip Code
02139
Burton, Nicholas O; Dwivedi, Vivek K; Burkhart, Kirk B et al. (2018) Neurohormonal signaling via a sulfotransferase antagonizes insulin-like signaling to regulate a Caenorhabditis elegans stress response. Nat Commun 9:5152
Burton, Nicholas O; Furuta, Tokiko; Webster, Amy K et al. (2017) Insulin-like signalling to the maternal germline controls progeny response to osmotic stress. Nat Cell Biol 19:252-257
Luo, Shuo; Horvitz, H Robert (2017) The CDK8 Complex and Proneural Proteins Together Drive Neurogenesis from a Mesodermal Lineage. Curr Biol 27:661-672
Paquin, Nicolas; Murata, Yasunobu; Froehlich, Allan et al. (2016) The Conserved VPS-50 Protein Functions in Dense-Core Vesicle Maturation and Acidification and Controls Animal Behavior. Curr Biol 26:862-71
Bhatla, Nikhil; Droste, Rita; Sando, Steven R et al. (2015) Distinct Neural Circuits Control Rhythm Inhibition and Spitting by the Myogenic Pharynx of C. elegans. Curr Biol 25:2075-89
Ma, Dengke K; Li, Zhijie; Lu, Alice Y et al. (2015) Acyl-CoA Dehydrogenase Drives Heat Adaptation by Sequestering Fatty Acids. Cell 161:1152-1163
Bhatla, Nikhil; Horvitz, H Robert (2015) Light and hydrogen peroxide inhibit C. elegans Feeding through gustatory receptor orthologs and pharyngeal neurons. Neuron 85:804-18
de la Cruz, Ignacio Perez; Ma, Long; Horvitz, H Robert (2014) The Caenorhabditis elegans iodotyrosine deiodinase ortholog SUP-18 functions through a conserved channel SC-box to regulate the muscle two-pore domain potassium channel SUP-9. PLoS Genet 10:e1004175
Ma, Dengke K; Rothe, Michael; Zheng, Shu et al. (2013) Cytochrome P450 drives a HIF-regulated behavioral response to reoxygenation by C. elegans. Science 341:554-8
Ma, Long; Gao, Xiaoyang; Luo, Jintao et al. (2012) The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. PLoS Genet 8:e1002827

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