Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM024971-27
Application #
6794047
Study Section
Special Emphasis Panel (NSS)
Program Officer
Shapiro, Bert I
Project Start
1978-04-01
Project End
2006-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
27
Fiscal Year
2004
Total Cost
$335,266
Indirect Cost

  Institution

Name
State University New York Stony Brook
Department
Physiology
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794

  Publications

Sengupta, Parijat; Bosis, Eran; Nachliel, Esther et al. (2009) EGFR juxtamembrane domain, membranes, and calmodulin: kinetics of their interaction. Biophys J 96:4887-95
Golebiewska, Urszula; Nyako, Marian; Woturski, William et al. (2008) Diffusion coefficient of fluorescent phosphatidylinositol 4,5-bisphosphate in the plasma membrane of cells. Mol Biol Cell 19:1663-9
Sengupta, Parijat; Ruano, Maria Jose; Tebar, Francesc et al. (2007) Membrane-permeable calmodulin inhibitors (e.g. W-7/W-13) bind to membranes, changing the electrostatic surface potential: dual effect of W-13 on epidermal growth factor receptor activation. J Biol Chem 282:8474-86
Nomikos, Michail; Mulgrew-Nesbitt, Anna; Pallavi, Payal et al. (2007) Binding of phosphoinositide-specific phospholipase C-zeta (PLC-zeta) to phospholipid membranes: potential role of an unstructured cluster of basic residues. J Biol Chem 282:16644-53
Sato, Takeshi; Pallavi, Payal; Golebiewska, Urszula et al. (2006) Structure of the membrane reconstituted transmembrane-juxtamembrane peptide EGFR(622-660) and its interaction with Ca2+/calmodulin. Biochemistry 45:12704-14
Golebiewska, Urszula; Gambhir, Alok; Hangyas-Mihalyne, Gyongyi et al. (2006) Membrane-bound basic peptides sequester multivalent (PIP2), but not monovalent (PS), acidic lipids. Biophys J 91:588-99
Tao, Jiangchuan; Shumay, Elena; McLaughlin, Stuart et al. (2006) Regulation of AKAP-membrane interactions by calcium. J Biol Chem 281:23932-44
McLaughlin, Stuart; Smith, Steven O; Hayman, Michael J et al. (2005) An electrostatic engine model for autoinhibition and activation of the epidermal growth factor receptor (EGFR/ErbB) family. J Gen Physiol 126:41-53
Wang, Jiyao; Gambhir, Alok; McLaughlin, Stuart et al. (2004) A computational model for the electrostatic sequestration of PI(4,5)P2 by membrane-adsorbed basic peptides. Biophys J 86:1969-86
Gambhir, Alok; Hangyas-Mihalyne, Gyongyi; Zaitseva, Irina et al. (2004) Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins. Biophys J 86:2188-207

Showing the most recent 10 out of 55 publications