Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM025766-36
Application #
2021802
Study Section
Special Emphasis Panel (NSS)
Project Start
1978-09-01
Project End
1998-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
36
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Duke University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
071723621
City
Durham
State
NC
Country
United States
Zip Code
27705
Perez-Vilar, J; Eckhardt, A E; DeLuca, A et al. (1998) Porcine submaxillary mucin forms disulfide-linked multimers through its amino-terminal D-domains. J Biol Chem 273:14442-9
Perez-Vilar, J; Eckhardt, A E; Hill, R L (1996) Porcine submaxillary mucin forms disulfide-bonded dimers between its carboxyl-terminal domains. J Biol Chem 271:9845-50
Roth, J; Wang, Y; Eckhardt, A E et al. (1994) Subcellular localization of the UDP-N-acetyl-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase-mediated O-glycosylation reaction in the submaxillary gland. Proc Natl Acad Sci U S A 91:8935-9
Wang, Y; Agrwal, N; Eckhardt, A E et al. (1993) The acceptor substrate specificity of porcine submaxillary UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase is dependent on the amino acid sequences adjacent to serine and threonine residues. J Biol Chem 268:22979-83
Wang, Y; Abernethy, J L; Eckhardt, A E et al. (1992) Purification and characterization of a UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase specific for glycosylation of threonine residues. J Biol Chem 267:12709-16
Tiemeyer, M; Brandley, B K; Ishihara, M et al. (1992) The binding specificity of normal and variant rat Kupffer cell (lectin) receptors expressed in COS cells. J Biol Chem 267:12252-7
Eckhardt, A E; Timpte, C S; Abernethy, J L et al. (1991) Porcine submaxillary mucin contains a cystine-rich, carboxyl-terminal domain in addition to a highly repetitive, glycosylated domain. J Biol Chem 266:9678-86
Hoyle, G W; Hill, R L (1991) Structure of the gene for a carbohydrate-binding receptor unique to rat kupffer cells. J Biol Chem 266:1850-7
Timpte, C S; Eckhardt, A E; Abernethy, J L et al. (1988) Porcine submaxillary gland apomucin contains tandemly repeated, identical sequences of 81 residues. J Biol Chem 263:1081-8
Hoyle, G W; Hill, R L (1988) Molecular cloning and sequencing of a cDNA for a carbohydrate binding receptor unique to rat Kupffer cells. J Biol Chem 263:7487-92

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