Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM026154-26
Application #
2174627
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
26
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Biochemistry
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Herbert, Kristina M; Sarkar, Susanta K; Mills, Maria et al. (2016) A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting. RNA 22:175-83
Brown, Jessica A; Kinzig, Charles G; DeGregorio, Suzanne J et al. (2016) Hoogsteen-position pyrimidines promote the stability and function of the MALAT1 RNA triple helix. RNA 22:743-9
Vilborg, Anna; Passarelli, Maria C; Yario, Therese A et al. (2015) Widespread Inducible Transcription Downstream of Human Genes. Mol Cell 59:449-61
Brown, Jessica A; Bulkley, David; Wang, Jimin et al. (2014) Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix. Nat Struct Mol Biol 21:633-40
Xie, Mingyi; Steitz, Joan A (2014) Versatile microRNA biogenesis in animals and their viruses. RNA Biol 11:673-81
Riley, Kasandra J; Steitz, Joan A (2013) The ""Observer Effect"" in genome-wide surveys of protein-RNA interactions. Mol Cell 49:601-4
Herbert, Kristina M; Pimienta, Genaro; DeGregorio, Suzanne J et al. (2013) Phosphorylation of DGCR8 increases its intracellular stability and induces a progrowth miRNA profile. Cell Rep 5:1070-81
Nag, Anita; Steitz, Joan A (2012) Tri-snRNP-associated proteins interact with subunits of the TRAMP and nuclear exosome complexes, linking RNA decay and pre-mRNA splicing. RNA Biol 9:334-42
Alexandrov, Andrei; Colognori, David; Shu, Mei-Di et al. (2012) Human spliceosomal protein CWC22 plays a role in coupling splicing to exon junction complex deposition and nonsense-mediated decay. Proc Natl Acad Sci U S A 109:21313-8
Brown, Jessica A; Valenstein, Max L; Yario, Therese A et al. (2012) Formation of triple-helical structures by the 3'-end sequences of MALAT1 and MEN? noncoding RNAs. Proc Natl Acad Sci U S A 109:19202-7

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