Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM026444-18
Application #
2174715
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-04-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
18
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Salk Institute for Biological Studies
Department
Type
DUNS #
005436803
City
La Jolla
State
CA
Country
United States
Zip Code
92037
Kao, H Y; Verdel, A; Tsai, C C et al. (2001) Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7. J Biol Chem 276:47496-507
Ghbeish, N; Tsai, C C; Schubiger, M et al. (2001) The dual role of ultraspiracle, the Drosophila retinoid X receptor, in the ecdysone response. Proc Natl Acad Sci U S A 98:3867-72
Doucas, V; Shi, Y; Miyamoto, S et al. (2000) Cytoplasmic catalytic subunit of protein kinase A mediates cross-repression by NF-kappa B and the glucocorticoid receptor. Proc Natl Acad Sci U S A 97:11893-8
Kao, H Y; Downes, M; Ordentlich, P et al. (2000) Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression. Genes Dev 14:55-66
Doucas, V; Tini, M; Egan, D A et al. (1999) Modulation of CREB binding protein function by the promyelocytic (PML) oncoprotein suggests a role for nuclear bodies in hormone signaling. Proc Natl Acad Sci U S A 96:2627-32
Nagy, L; Kao, H Y; Love, J D et al. (1999) Mechanism of corepressor binding and release from nuclear hormone receptors. Genes Dev 13:3209-16
Chen, H; Lin, R J; Xie, W et al. (1999) Regulation of hormone-induced histone hyperacetylation and gene activation via acetylation of an acetylase. Cell 98:675-86
Doucas, V; Evans, R M (1999) Human T-cell leukemia retrovirus-Tax protein is a repressor of nuclear receptor signaling. Proc Natl Acad Sci U S A 96:2633-8
Tsai, C C; Kao, H Y; Yao, T P et al. (1999) SMRTER, a Drosophila nuclear receptor coregulator, reveals that EcR-mediated repression is critical for development. Mol Cell 4:175-86
Kao, H Y; Ordentlich, P; Koyano-Nakagawa, N et al. (1998) A histone deacetylase corepressor complex regulates the Notch signal transduction pathway. Genes Dev 12:2269-77

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