Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM028962-16
Application #
2175340
Study Section
Metallobiochemistry Study Section (BMT)
Project Start
1990-04-01
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
16
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Bhadra, Mayukh; Lee, Jung Yoon C; Cowley, Ryan E et al. (2018) Intramolecular Hydrogen Bonding Enhances Stability and Reactivity of Mononuclear Cupric Superoxide Complexes. J Am Chem Soc 140:9042-9045
López, Isidoro; Cao, Rui; Quist, David A et al. (2017) Direct Determination of Electron-Transfer Properties of Dicopper-Bound Reduced Dioxygen Species by a Cryo-Spectroelectrochemical Approach. Chemistry 23:18314-18319
Cao, Rui; Elrod, Lee Taylor; Lehane, Ryan L et al. (2016) A Peroxynitrite Dicopper Complex: Formation via Cu-NO and Cu-O2 Intermediates and Reactivity via O-O Cleavage Chemistry. J Am Chem Soc 138:16148-16158
Liu, Jeffrey J; Diaz, Daniel E; Quist, David A et al. (2016) Copper(I)-Dioxygen Adducts and Copper Enzyme Mechanisms. Isr J Chem 56:9-10
Garcia-Bosch, Isaac; Cowley, Ryan E; Díaz, Daniel E et al. (2016) Dioxygen Activation by a Macrocyclic Copper Complex Leads to a Cu2O2 Core with Unexpected Structure and Reactivity. Chemistry 22:5133-7
Cao, Rui; Saracini, Claudio; Ginsbach, Jake W et al. (2016) Peroxo and Superoxo Moieties Bound to Copper Ion: Electron-Transfer Equilibrium with a Small Reorganization Energy. J Am Chem Soc 138:7055-66
Kim, Sunghee; Lee, Jung Yoon; Cowley, Ryan E et al. (2015) A N3S(thioether)-ligated Cu(II)-superoxo with enhanced reactivity. J Am Chem Soc 137:2796-9
Lee, Jung Yoon; Karlin, Kenneth D (2015) Elaboration of copper-oxygen mediated C-H activation chemistry in consideration of future fuel and feedstock generation. Curr Opin Chem Biol 25:184-93
Kim, Sunghee; Ginsbach, Jake W; Lee, Jung Yoon et al. (2015) Amine oxidative N-dealkylation via cupric hydroperoxide Cu-OOH homolytic cleavage followed by site-specific fenton chemistry. J Am Chem Soc 137:2867-74
Kim, Sunghee; Ginsbach, Jake W; Billah, A Imtiaz et al. (2014) Tuning of the copper-thioether bond in tetradentate N?S(thioether) ligands; O-O bond reductive cleavage via a [Cu(II)?(?-1,2-peroxo)]²?/[Cu(III)?(?-oxo)?]²? equilibrium. J Am Chem Soc 136:8063-71

Showing the most recent 10 out of 88 publications