Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM030804-26
Application #
2175924
Study Section
Special Emphasis Panel (NSS)
Project Start
1982-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
26
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Harvard University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
071723621
City
Cambridge
State
MA
Country
United States
Zip Code
02138

  Publications

Qi, Yan; Nam, Kwangho; Spong, Marie C et al. (2012) Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc Natl Acad Sci U S A 109:1086-91
Crenshaw, Charisse M; Nam, Kwangho; Oo, Kimberly et al. (2012) Enforced presentation of an extrahelical guanine to the lesion recognition pocket of human 8-oxoguanine glycosylase, hOGG1. J Biol Chem 287:24916-28
Qi, Yan; Spong, Marie C; Nam, Kwangho et al. (2010) Entrapment and structure of an extrahelical guanine attempting to enter the active site of a bacterial DNA glycosylase, MutM. J Biol Chem 285:1468-78
Qi, Yan; Spong, Marie C; Nam, Kwangho et al. (2009) Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme. Nature 462:762-6
Nam, Kwangho; Verdine, Gregory L; Karplus, Martin (2009) Analysis of an anomalous mutant of MutM DNA glycosylase leads to new insights into the catalytic mechanism. J Am Chem Soc 131:18208-9