Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM032384-14
Application #
2176555
Study Section
Cellular Biology and Physiology Subcommittee 1 (CBY)
Project Start
1983-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Biochemistry
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Elvekrog, Margaret M; Walter, Peter (2015) Dynamics of co-translational protein targeting. Curr Opin Chem Biol 29:79-86
Noriega, Thomas R; Chen, Jin; Walter, Peter et al. (2014) Real-time observation of signal recognition particle binding to actively translating ribosomes. Elife 3:
Noriega, Thomas R; Tsai, Albert; Elvekrog, Margaret M et al. (2014) Signal recognition particle-ribosome binding is sensitive to nascent chain length. J Biol Chem 289:19294-305
Lin, Jonathan H; Li, Han; Zhang, Yuhong et al. (2009) Divergent effects of PERK and IRE1 signaling on cell viability. PLoS One 4:e4170
Reyes, Christopher L; Rutenber, Earl; Walter, Peter et al. (2007) X-ray structures of the signal recognition particle receptor reveal targeting cycle intermediates. PLoS One 2:e607
Shan, Shu-ou; Chandrasekar, Sowmya; Walter, Peter (2007) Conformational changes in the GTPase modules of the signal reception particle and its receptor drive initiation of protein translocation. J Cell Biol 178:611-20
Shan, Shu-ou; Walter, Peter (2005) Molecular crosstalk between the nucleotide specificity determinant of the SRP GTPase and the SRP receptor. Biochemistry 44:6214-22
Credle, Joel J; Finer-Moore, Janet S; Papa, Feroz R et al. (2005) On the mechanism of sensing unfolded protein in the endoplasmic reticulum. Proc Natl Acad Sci U S A 102:18773-84
Shan, Shu-ou; Walter, Peter (2003) Induced nucleotide specificity in a GTPase. Proc Natl Acad Sci U S A 100:4480-5
Papa, Feroz R; Zhang, Chao; Shokat, Kevan et al. (2003) Bypassing a kinase activity with an ATP-competitive drug. Science 302:1533-7

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