Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM036278-12
Application #
2178268
Study Section
Microbial Physiology and Genetics Subcommittee 2 (MBC)
Project Start
1986-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Dentistry
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Guo, Monica S; Updegrove, Taylor B; Gogol, Emily B et al. (2014) MicL, a new ?E-dependent sRNA, combats envelope stress by repressing synthesis of Lpp, the major outer membrane lipoprotein. Genes Dev 28:1620-34
Lim, Bentley; Miyazaki, Ryoji; Neher, Saskia et al. (2013) Heat shock transcription factor ?32 co-opts the signal recognition particle to regulate protein homeostasis in E. coli. PLoS Biol 11:e1001735
Lima, Santiago; Guo, Monica S; Chaba, Rachna et al. (2013) Dual molecular signals mediate the bacterial response to outer-membrane stress. Science 340:837-41
Chaba, Rachna; Alba, Benjamin M; Guo, Monica S et al. (2011) Signal integration by DegS and RseB governs the σ E-mediated envelope stress response in Escherichia coli. Proc Natl Acad Sci U S A 108:2106-11
de Almeida, Alejandra; Catone, Mariela V; Rhodius, Virgil A et al. (2011) Unexpected stress-reducing effect of PhaP, a poly(3-hydroxybutyrate) granule-associated protein, in Escherichia coli. Appl Environ Microbiol 77:6622-9
Koo, Byoung-Mo; Rhodius, Virgil A; Campbell, Elizabeth A et al. (2009) Dissection of recognition determinants of Escherichia coli sigma32 suggests a composite -10 region with an 'extended -10' motif and a core -10 element. Mol Microbiol 72:815-29
Koo, Byoung-Mo; Rhodius, Virgil A; Campbell, Elizabeth A et al. (2009) Mutational analysis of Escherichia coli sigma28 and its target promoters reveals recognition of a composite -10 region, comprised of an 'extended -10' motif and a core -10 element. Mol Microbiol 72:830-43
Guisbert, Eric; Yura, Takashi; Rhodius, Virgil A et al. (2008) Convergence of molecular, modeling, and systems approaches for an understanding of the Escherichia coli heat shock response. Microbiol Mol Biol Rev 72:545-54
Yura, Takashi; Guisbert, Eric; Poritz, Mark et al. (2007) Analysis of sigma32 mutants defective in chaperone-mediated feedback control reveals unexpected complexity of the heat shock response. Proc Natl Acad Sci U S A 104:17638-43
Grigorova, Irina L; Phleger, Naum J; Mutalik, Vivek K et al. (2006) Insights into transcriptional regulation and sigma competition from an equilibrium model of RNA polymerase binding to DNA. Proc Natl Acad Sci U S A 103:5332-7

Showing the most recent 10 out of 50 publications