Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM036700-19
Application #
6700765
Study Section
Special Emphasis Panel (NSS)
Program Officer
Schwab, John M
Project Start
1986-02-01
Project End
2006-01-31
Budget Start
2004-02-01
Budget End
2005-01-31
Support Year
19
Fiscal Year
2004
Total Cost
$249,429
Indirect Cost
Name
University of California Los Angeles
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Lam, Yu-Hong; Grayson, Matthew N; Holland, Mareike C et al. (2016) Theory and Modeling of Asymmetric Catalytic Reactions. Acc Chem Res 49:750-62
Hie, Liana; Fine Nathel, Noah F; Hong, Xin et al. (2016) Nickel-Catalyzed Activation of Acyl C-O Bonds of Methyl Esters. Angew Chem Int Ed Engl 55:2810-4
Hie, Liana; Fine Nathel, Noah F; Shah, Tejas K et al. (2015) Conversion of amides to esters by the nickel-catalysed activation of amide C-N bonds. Nature 524:79-83
Lam, Yu-Hong; Houk, K N (2015) Origins of stereoselectivity in intramolecular aldol reactions catalyzed by cinchona amines. J Am Chem Soc 137:2116-27
Patel, Ashay; Vella, Joseph R; Ma, Zhi-Xiong et al. (2015) Transition State Gauche Effects Control the Torquoselectivities of the Electrocyclizations of Chiral 1-Azatrienes. J Org Chem 80:11888-94
Noey, Elizabeth L; Tibrewal, Nidhi; Jiménez-Osés, Gonzalo et al. (2015) Origins of stereoselectivity in evolved ketoreductases. Proc Natl Acad Sci U S A 112:E7065-72
Krenske, Elizabeth H; Lam, Sarah; Ng, Jerome P L et al. (2015) Concerted Ring Opening and Cycloaddition of Chiral Epoxy Enolsilanes with Dienes. Angew Chem Int Ed Engl 54:7422-5
Osuna, Sílvia; Jiménez-Osés, Gonzalo; Noey, Elizabeth L et al. (2015) Molecular dynamics explorations of active site structure in designed and evolved enzymes. Acc Chem Res 48:1080-9
Phillips, Eric M; Mesganaw, Tehetena; Patel, Ashay et al. (2015) Synthesis of ent-ketorfanol via a C-H alkenylation/torquoselective 6? electrocyclization cascade. Angew Chem Int Ed Engl 54:12044-8
Krenske, Elizabeth H; Houk, K N; Harmata, Michael (2015) Computational analysis of the stereochemical outcome in the imidazolidinone-catalyzed enantioselective (4 + 3)-cycloaddition reaction. J Org Chem 80:744-50

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