Project Start
1970-07-01
Project End
1998-05-31
Budget Start
1995-12-01
Budget End
1998-05-31
Support Year
26
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Hauptman-Woodward Medical Research Institute
Department
Type
DUNS #
074025479
City
Buffalo
State
NY
Country
United States
Zip Code
14203
Numazawa, Mitsuteru; Tachibana, Mii; Mutsumi, Ayako et al. (2002) Aromatization of 16alpha-hydroxyandrostenedione by human placental microsomes: effect of preincubation with suicide substrates of androstenedione aromatization. J Steroid Biochem Mol Biol 81:165-72
Kao, Y C; Higashiyama, T; Sun, X et al. (2000) Catalytic differences between porcine blastocyst and placental aromatase isozymes. Eur J Biochem 267:6134-9
Sawicki, M W; Ng, P C; Burkhart, B M et al. (1999) Structure of an activity suppressing Fab fragment to cytochrome P450 aromatase: insights into the antibody-antigen interactions. Mol Immunol 36:423-32
Kao, Y C; Higashiyama, T; Yarborough, C et al. (1999) Functional characterization of 102-amino acid-deleted form of human aromatase (delta102-aromatase). Steroids 64:422-9
Janulis, L; Bahr, J M; Hess, R A et al. (1998) Rat testicular germ cells and epididymal sperm contain active P450 aromatase. J Androl 19:65-71
Kitawaki, J; Noguchi, T; Amatsu, T et al. (1997) Expression of aromatase cytochrome P450 protein and messenger ribonucleic acid in human endometriotic and adenomyotic tissues but not in normal endometrium. Biol Reprod 57:514-9
Osawa, Y; Higashiyama, T; Toma, Y et al. (1997) Diverse function of aromatase and the N-terminal sequence deleted form. J Steroid Biochem Mol Biol 61:117-26
Albrecht, B A; Daels, P F (1997) Immunolocalization of 3 beta-hydroxysteroid dehydrogenase, cytochrome P450 17 alpha-hydroxylase/17,20-lyase and cytochrome P450 aromatase in the equine corpus luteum of dioestrus and early pregnancy. J Reprod Fertil 111:127-33
Ng, P C; Osawa, Y (1997) Preparation and characterization of the F (ab)2 fragments of an aromatase activity-suppressing monoclonal antibody. Steroids 62:776-81
Toma, Y; Higashiyama, T; Yarborough, C et al. (1996) Diverse functions of aromatase: O-deethylation of 7-ethoxycoumarin. Endocrinology 137:3791-6

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