Project Start
1978-05-01
Project End
1998-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Biochemistry
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Kim, D S; Szczypka, M S; Palmiter, R D (2000) Dopamine-deficient mice are hypersensitive to dopamine receptor agonists. J Neurosci 20:4405-13
Szczypka, M S; Rainey, M A; Palmiter, R D (2000) Dopamine is required for hyperphagia in Lep(ob/ob) mice. Nat Genet 25:102-4
Cho, M C; Rao, M; Koch, W J et al. (1999) Enhanced contractility and decreased beta-adrenergic receptor kinase-1 in mice lacking endogenous norepinephrine and epinephrine. Circulation 99:2702-7
Szczypka, M S; Mandel, R J; Donahue, B A et al. (1999) Viral gene delivery selectively restores feeding and prevents lethality of dopamine-deficient mice. Neuron 22:167-78
Commins, S P; Marsh, D J; Thomas, S A et al. (1999) Norepinephrine is required for leptin effects on gene expression in brown and white adipose tissue. Endocrinology 140:4772-8
Szczypka, M S; Rainey, M A; Kim, D S et al. (1999) Feeding behavior in dopamine-deficient mice. Proc Natl Acad Sci U S A 96:12138-43
Szczypka, M S; Zhou, Q Y; Palmiter, R D (1998) Dopamine-stimulated sexual behavior is testosterone dependent in mice. Behav Neurosci 112:1229-35
Thomas, S A; Marck, B T; Palmiter, R D et al. (1998) Restoration of norepinephrine and reversal of phenotypes in mice lacking dopamine beta-hydroxylase. J Neurochem 70:2468-76
Tafari, A T; Thomas, S A; Palmiter, R D (1997) Norepinephrine facilitates the development of the murine sweat response but is not essential. J Neurosci 17:4275-81
Thomas, S A; Palmiter, R D (1997) Impaired maternal behavior in mice lacking norepinephrine and epinephrine. Cell 91:583-92

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