Funding Agency

Agency
National Institute of Health (NIH)
Institute
Eunice Kennedy Shriver National Institute of Child Health & Human Development (NICHD)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HD016910-15
Application #
2197384
Study Section
Endocrinology Study Section (END)
Project Start
1982-08-01
Project End
1998-05-31
Budget Start
1996-06-01
Budget End
1997-05-31
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of North Carolina Chapel Hill
Department
Pediatrics
Type
Schools of Medicine
DUNS #
078861598
City
Chapel Hill
State
NC
Country
United States
Zip Code
27599

  Publications

Tan, Jiann-An; Bai, Suxia; Grossman, Gail et al. (2014) Mechanism of androgen receptor corepression by CK?BP2/CRIF1, a multifunctional transcription factor coregulator expressed in prostate cancer. Mol Cell Endocrinol 382:302-313
Su, Shifeng; Minges, John T; Grossman, Gail et al. (2013) Proto-oncogene activity of melanoma antigen-A11 (MAGE-A11) regulates retinoblastoma-related p107 and E2F1 proteins. J Biol Chem 288:24809-24
Minges, John T; Su, Shifeng; Grossman, Gail et al. (2013) Melanoma antigen-A11 (MAGE-A11) enhances transcriptional activity by linking androgen receptor dimers. J Biol Chem 288:1939-52
Askew, Emily B; Minges, John T; Hnat, Andrew T et al. (2012) Structural features discriminate androgen receptor N/C terminal and coactivator interactions. Mol Cell Endocrinol 348:403-10
Cherian, Milu T; Wilson, Elizabeth M; Shapiro, David J (2012) A competitive inhibitor that reduces recruitment of androgen receptor to androgen-responsive genes. J Biol Chem 287:23368-80
Titus, Mark A; Zeithaml, Brian; Kantor, Boris et al. (2012) Dominant-negative androgen receptor inhibition of intracrine androgen-dependent growth of castration-recurrent prostate cancer. PLoS One 7:e30192
Su, Shifeng; Blackwelder, Amanda J; Grossman, Gail et al. (2012) Primate-specific melanoma antigen-A11 regulates isoform-specific human progesterone receptor-B transactivation. J Biol Chem 287:34809-24
Lagarde, William H; Blackwelder, Amanda J; Minges, John T et al. (2012) Androgen receptor exon 1 mutation causes androgen insensitivity by creating phosphorylation site and inhibiting melanoma antigen-A11 activation of NH2- and carboxyl-terminal interaction-dependent transactivation. J Biol Chem 287:10905-15
Liu, Qiang; Su, Shifeng; Blackwelder, Amanda J et al. (2011) Gain in transcriptional activity by primate-specific coevolution of melanoma antigen-A11 and its interaction site in androgen receptor. J Biol Chem 286:29951-63
Mohler, James L; Titus, Mark A; Bai, Suxia et al. (2011) Activation of the androgen receptor by intratumoral bioconversion of androstanediol to dihydrotestosterone in prostate cancer. Cancer Res 71:1486-96

Showing the most recent 10 out of 15 publications