Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL008508-32
Application #
2213281
Study Section
Special Emphasis Panel (NSS)
Project Start
1976-01-01
Project End
1996-12-31
Budget Start
1995-01-01
Budget End
1996-12-31
Support Year
32
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Pharmacology
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Ren, X L; Hoffman, B F (1994) Reversibility of electrophysiologic abnormalities of subendocardial Purkinje fibers induced by ischemia. J Cardiovasc Electrophysiol 5:412-21
Yao, J A; Tseng, G N (1994) Modulation of 4-AP block of a mammalian A-type K channel clone by channel gating and membrane voltage. Biophys J 67:130-42
Hoffman, B F; Ren, X L (1994) Reversibility of electrophysiological abnormalities in subacute ischemia. Pacing Clin Electrophysiol 17:2095-9
Tseng-Crank, J; Yao, J A; Berman, M F et al. (1993) Functional role of the NH2-terminal cytoplasmic domain of a mammalian A-type K channel. J Gen Physiol 102:1057-83
Sorota, S (1992) Swelling-induced chloride-sensitive current in canine atrial cells revealed by whole-cell patch-clamp method. Circ Res 70:679-87
Spinelli, W; Sorota, S; Siegal, M et al. (1991) Antiarrhythmic actions of the ATP-regulated K+ current activated by pinacidil. Circ Res 68:1127-37
Tseng, G N; Hoffman, B F (1990) Actions of pinacidil on membrane currents in canine ventricular myocytes and their modulation by intracellular ATP and cAMP. Pflugers Arch 415:414-24
Tseng, G N; Boyden, P A (1989) Multiple types of Ca2+ currents in single canine Purkinje cells. Circ Res 65:1735-50
Tseng, G N; Hoffman, B F (1989) Two components of transient outward current in canine ventricular myocytes. Circ Res 64:633-47
Tseng, G N (1988) Calcium current restitution in mammalian ventricular myocytes is modulated by intracellular calcium. Circ Res 63:468-82

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