Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL011551-29
Application #
2214658
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-05-01
Project End
1997-12-01
Budget Start
1996-05-01
Budget End
1997-12-01
Support Year
29
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Syracuse University
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
002257350
City
Syracuse
State
NY
Country
United States
Zip Code
13244
Samuel, D S; Ewton, D Z; Coolican, S A et al. (1999) Raf-1 activation stimulates proliferation and inhibits IGF-stimulated differentiation in L6A1 myoblasts. Horm Metab Res 31:55-64
Ewton, D Z; Coolican, S A; Mohan, S et al. (1998) Modulation of insulin-like growth factor actions in L6A1 myoblasts by insulin-like growth factor binding protein (IGFBP)-4 and IGFBP-5: a dual role for IGFBP-5. J Cell Physiol 177:47-57
Coolican, S A; Samuel, D S; Ewton, D Z et al. (1997) The mitogenic and myogenic actions of insulin-like growth factors utilize distinct signaling pathways. J Biol Chem 272:6653-62
Florini, J R; Ewton, D Z; Coolican, S A (1996) Growth hormone and the insulin-like growth factor system in myogenesis. Endocr Rev 17:481-517
Florini, J R; Samuel, D S; Ewton, D Z et al. (1996) Stimulation of myogenic differentiation by a neuregulin, glial growth factor 2. Are neuregulins the long-sought muscle trophic factors secreted by nerves? J Biol Chem 271:12699-702
Florini, J R; Ewton, D Z (1995) Actions of anabolic hormones and growth factors on cultured neonatal heart cells. Growth Regul 5:28-35
Ewton, D Z; Florini, J R (1995) IGF binding proteins-4, -5 and -6 may play specialized roles during L6 myoblast proliferation and differentiation. J Endocrinol 144:539-53
Bosche, W J; Ewton, D Z; Florini, J R (1995) Transforming growth factor-beta isoform expression in insulin-like growth factor stimulated myogenesis. J Cell Physiol 164:324-33
Ewton, D Z; Roof, S L; Magri, K A et al. (1994) IGF-II is more active than IGF-I in stimulating L6A1 myogenesis: greater mitogenic actions of IGF-I delay differentiation. J Cell Physiol 161:277-84
Florini, J R; Ewton, D Z; Magri, K A et al. (1993) IGFs and muscle differentiation. Adv Exp Med Biol 343:319-26

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