Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL012792-27
Application #
2214694
Study Section
Special Emphasis Panel (NSS)
Project Start
1979-01-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
27
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Virginia
Department
Physiology
Type
Schools of Medicine
DUNS #
001910777
City
Charlottesville
State
VA
Country
United States
Zip Code
22904
Liao, Yongbo; Regan, Christopher P; Manabe, Ichiro et al. (2007) Smooth muscle-targeted knockout of connexin43 enhances neointimal formation in response to vascular injury. Arterioscler Thromb Vasc Biol 27:1037-42
Calera, Monica R; Topley, Heather L; Liao, Yongbo et al. (2006) Connexin43 is required for production of the aqueous humor in the murine eye. J Cell Sci 119:4510-9
Platts, Steven H; Duling, Brian R (2004) Adenosine A3 receptor activation modulates the capillary endothelial glycocalyx. Circ Res 94:77-82
Figueroa, Xavier F; Paul, David L; Simon, Alexander M et al. (2003) Central role of connexin40 in the propagation of electrically activated vasodilation in mouse cremasteric arterioles in vivo. Circ Res 92:793-800
Yashiro, Yasuaki; Duling, Brian R (2003) Participation of intracellular Ca2+ stores in arteriolar conducted responses. Am J Physiol Heart Circ Physiol 285:H65-73
Liao, Y; Duling, B R (2001) Possible cytotoxic effect of the expression of a connexin 43-LacZ fusion gene in cells of the vascular wall. J Vasc Res 38:203-11
Liao, Y; Day, K H; Damon, D N et al. (2001) Endothelial cell-specific knockout of connexin 43 causes hypotension and bradycardia in mice. Proc Natl Acad Sci U S A 98:9989-94
Matsuki, T; Duling, B R (2000) TNF-alpha modulates arteriolar reactivity secondary to a change in intimal permeability. Microcirculation 7:411-8
Henry, C B; Duling, B R (2000) TNF-alpha increases entry of macromolecules into luminal endothelial cell glycocalyx. Am J Physiol Heart Circ Physiol 279:H2815-23
Yashiro, Y; Duling, B R (2000) Integrated Ca(2+) signaling between smooth muscle and endothelium of resistance vessels. Circ Res 87:1048-54

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