Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
7R37HL028947-09
Application #
3485956
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1981-12-01
Project End
1991-09-29
Budget Start
1989-07-01
Budget End
1989-09-29
Support Year
9
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Cor Therapeutics, Inc.
Department
Type
DUNS #
City
South San Francisco
State
CA
Country
United States
Zip Code
94080
Parise, L V; Steiner, B; Nannizzi, L et al. (1993) Evidence for novel binding sites on the platelet glycoprotein IIb and IIIa subunits and immobilized fibrinogen. Biochem J 289 ( Pt 2):445-51
Phillips, D R (1992) Surface labeling of platelet membrane glycoproteins. Methods Enzymol 215:412-9
Phillips, D R; Fitzgerald, L; Parise, L et al. (1992) Platelet membrane glycoprotein IIb-IIIa complex: purification, characterization, and reconstitution into phospholipid vesicles. Methods Enzymol 215:244-63
Lanza, F; Wolf, D; Fox, C F et al. (1991) cDNA cloning and expression of platelet p24/CD9. Evidence for a new family of multiple membrane-spanning proteins. J Biol Chem 266:10638-45
Steiner, B; Parise, L V; Leung, B et al. (1991) Ca(2+)-dependent structural transitions of the platelet glycoprotein IIb-IIIa complex. Preparation of stable glycoprotein IIb and IIIa monomers. J Biol Chem 266:14986-91
Lanza, F; Kieffer, N; Phillips, D R et al. (1990) Characterization of the human platelet glycoprotein IIIa gene. Comparison with the fibronectin receptor beta-subunit gene. J Biol Chem 265:18098-103
Sosnoski, D M; Emanuel, B S; Hawkins, A L et al. (1988) Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa. J Clin Invest 81:1993-8
Fitzgerald, L A; Phillips, D R (1988) The molecular biology of platelet and endothelial cell adhesion receptors. Prog Clin Biol Res 283:387-418
Smart, J L; Deth, R C (1988) Influence of alpha 1-adrenergic receptor stimulation and phorbol esters on hepatic Na+/K+-ATPase activity. Pharmacology 37:94-104
Phillips, D R; Charo, I F; Parise, L V et al. (1988) The platelet membrane glycoprotein IIb-IIIa complex. Blood 71:831-43

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