Functions of Pulmonary Alveolar Type II Cells in Vitro

Mason, Robert James

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Method to Extend Research in Time (MERIT) Award (R37)
• Project #: 4R37HL029891-14
• Application #: 2216536
• Study Section: Special Emphasis Panel (NSS)
• Project Start: 1983-01-01
• Project End: 2000-12-31
• Budget Start: 1996-01-01
• Budget End: 1996-12-31
• Support Year: 14
• Fiscal Year: 1996

Institution

• Name: National Jewish Health
• City: Denver
• State: CO
• Country: United States
• Zip Code: 80206

Publications

Bridges, James P; Lin, Sui; Ikegami, Machiko et al. (2012) Conditional hypoxia inducible factor-1? induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol 362:24-41

Kosmider, Beata; Messier, Elise M; Chu, Hong Wei et al. (2011) Human alveolar epithelial cell injury induced by cigarette smoke. PLoS One 6:e26059

Finigan, James H; Faress, Jihane A; Wilkinson, Emily et al. (2011) Neuregulin-1-human epidermal receptor-2 signaling is a central regulator of pulmonary epithelial permeability and acute lung injury. J Biol Chem 286:10660-70

Ito, Yoko; Ahmad, Aftab; Kewley, Emily et al. (2011) Hypoxia-inducible factor regulates expression of surfactant protein in alveolar type II cells in vitro. Am J Respir Cell Mol Biol 45:938-45

Kosmider, Beata; Loader, Joan E; Murphy, Robert C et al. (2010) Apoptosis induced by ozone and oxysterols in human alveolar epithelial cells. Free Radic Biol Med 48:1513-24

Ito, Yoko; Mason, Robert J (2010) The effect of interleukin-13 (IL-13) and interferon-ýý (IFN-ýý) on expression of surfactant proteins in adult human alveolar type II cells in vitro. Respir Res 11:157

Bridges, James P; Ikegami, Machiko; Brilli, Lauren L et al. (2010) LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice. J Clin Invest 120:1736-48

Cao, Yuxia; Vo, Tiffany; Millien, Guetchyn et al. (2010) Epigenetic mechanisms modulate thyroid transcription factor 1-mediated transcription of the surfactant protein B gene. J Biol Chem 285:2152-64

Wang, Jieru; Oberley-Deegan, Rebecca; Wang, Shuanglin et al. (2009) Differentiated human alveolar type II cells secrete antiviral IL-29 (IFN-lambda 1) in response to influenza A infection. J Immunol 182:1296-304

Manzer, Rizwan; Dinarello, Charles A; McConville, Glen et al. (2008) Ozone exposure of macrophages induces an alveolar epithelial chemokine response through IL-1alpha. Am J Respir Cell Mol Biol 38:318-23