Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37HL031069-17
Application #
6088593
Study Section
Special Emphasis Panel (NSS)
Program Officer
Garfinkel, Susan J
Project Start
1984-04-01
Project End
2005-12-31
Budget Start
2001-01-25
Budget End
2001-12-31
Support Year
17
Fiscal Year
2001
Total Cost
$222,320
Indirect Cost
Name
New York Medical College
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Valhalla
State
NY
Country
United States
Zip Code
10595
Neo, Boon Hwa; Patel, Dhara; Kandhi, Sharath et al. (2013) Roles for cytosolic NADPH redox in regulating pulmonary artery relaxation by thiol oxidation-elicited subunit dimerization of protein kinase G1?. Am J Physiol Heart Circ Physiol 305:H330-43
Chettimada, Sukrutha; Rawat, Dhwajbahadur K; Dey, Nupur et al. (2012) Glc-6-PD and PKG contribute to hypoxia-induced decrease in smooth muscle cell contractile phenotype proteins in pulmonary artery. Am J Physiol Lung Cell Mol Physiol 303:L64-74
Wolin, Michael S (2012) Novel role for the regulation of mitochondrial fission by hypoxia inducible factor-1? in the control of smooth muscle remodeling and progression of pulmonary hypertension. Circ Res 110:1395-7
Gupte, Sachin A; Wolin, Michael S (2012) Relationships between vascular oxygen sensing mechanisms and hypertensive disease processes. Hypertension 60:269-75
Neo, Boon Hwa; Kandhi, Sharath; Wolin, Michael S (2011) Roles for redox mechanisms controlling protein kinase G in pulmonary and coronary artery responses to hypoxia. Am J Physiol Heart Circ Physiol 301:H2295-304
Wolin, Michael S (2011) Plasma glutathione peroxidase activity is potentially a key regulator of vascular disease-associated thrombosis. Circulation 123:1923-4
Wolin, Michael S (2010) Novel imaging approaches provide new windows to view subcellular changes in the redox state of smooth muscle cells. Circ Res 106:432-3
Neo, Boon Hwa; Kandhi, Sharath; Wolin, Michael S (2010) Roles for soluble guanylate cyclase and a thiol oxidation-elicited subunit dimerization of protein kinase G in pulmonary artery relaxation to hydrogen peroxide. Am J Physiol Heart Circ Physiol 299:H1235-41
Wolin, Michael S; Gupte, Sachin A; Mingone, Christopher J et al. (2010) Redox regulation of responses to hypoxia and NO-cGMP signaling in pulmonary vascular pathophysiology. Ann N Y Acad Sci 1203:126-32
Ahmad, Mansoor; Kelly, Melissa R; Zhao, Xiangmin et al. (2010) Roles for Nox4 in the contractile response of bovine pulmonary arteries to hypoxia. Am J Physiol Heart Circ Physiol 298:H1879-88

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