Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37HL031102-06
Application #
3486013
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1983-07-01
Project End
1993-06-30
Budget Start
1988-07-01
Budget End
1989-06-30
Support Year
6
Fiscal Year
1988
Total Cost
Indirect Cost
Name
Barnes-Jewish Hospital
Department
Type
DUNS #
City
Saint Louis
State
MO
Country
United States
Zip Code
63110
Herradon, Gonzalo; Ezquerra, Laura; Nguyen, Trang et al. (2005) Midkine regulates pleiotrophin organ-specific gene expression: evidence for transcriptional regulation and functional redundancy within the pleiotrophin/midkine developmental gene family. Biochem Biophys Res Commun 333:714-21
Pariser, Harold; Ezquerra, Laura; Herradon, Gonzalo et al. (2005) Fyn is a downstream target of the pleiotrophin/receptor protein tyrosine phosphatase beta/zeta-signaling pathway: regulation of tyrosine phosphorylation of Fyn by pleiotrophin. Biochem Biophys Res Commun 332:664-9
Liu, J J; Wang, Z Y; Deuel, T F et al. (1999) Imbalanced expression of functionally different WT1 isoforms may contribute to sporadic unilateral Wilms' tumor. Biochem Biophys Res Commun 254:197-9
Zhang, N; Yeh, H J; Zhong, R et al. (1999) A dominant-negative pleiotrophin mutant introduced by homologous recombination leads to germ-cell apoptosis in male mice. Proc Natl Acad Sci U S A 96:6734-8
Silos-Santiago, I; Yeh, H J; Gurrieri, M A et al. (1996) Localization of pleiotrophin and its mRNA in subpopulations of neurons and their corresponding axonal tracts suggests important roles in neural-glial interactions during development and in maturity. J Neurobiol 31:283-96
Kim, H R; Upadhyay, S; Li, G et al. (1995) Platelet-derived growth factor induces apoptosis in growth-arrested murine fibroblasts. Proc Natl Acad Sci U S A 92:9500-4
Wang, Z Y; Qiu, Q Q; Huang, J et al. (1995) Products of alternatively spliced transcripts of the Wilms' tumor suppressor gene, wt1, have altered DNA binding specificity and regulate transcription in different ways. Oncogene 10:415-22
Wang, Z Y; Qiu, Q Q; Gurrieri, M et al. (1995) WT1, the Wilms' tumor suppressor gene product, represses transcription through an interactive nuclear protein. Oncogene 10:1243-7
Wang, Z Y; Masaharu, N; Qiu, Q Q et al. (1994) An S1 nuclease-sensitive region in the first intron of human platelet-derived growth factor A-chain gene contains a negatively acting cell type-specific regulatory element. Nucleic Acids Res 22:457-64
Kawahara, R S; Deng, Z W; Denkinger, D J et al. (1994) Role of serine/threonine protein kinases in the induction of JE, a platelet-derived growth factor inducible gene. Biochem Biophys Res Commun 203:1815-20

Showing the most recent 10 out of 54 publications