Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37HL035610-12
Application #
2217863
Study Section
Experimental Cardiovascular Sciences Study Section (ECS)
Project Start
1985-09-30
Project End
1997-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Stanford University
Department
Surgery
Type
Schools of Medicine
DUNS #
800771545
City
Stanford
State
CA
Country
United States
Zip Code
94305

  Publications

Gnecchi, Massimiliano; He, Huamei; Melo, Luis G et al. (2009) Early beneficial effects of bone marrow-derived mesenchymal stem cells overexpressing Akt on cardiac metabolism after myocardial infarction. Stem Cells 27:971-9
Ip, James E; Wu, Yaojiong; Huang, Jing et al. (2007) Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. Mol Biol Cell 18:2873-82
Noiseux, Nicolas; Gnecchi, Massimiliano; Lopez-Ilasaca, Marco et al. (2006) Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation. Mol Ther 14:840-50
Gnecchi, Massimiliano; He, Huamei; Noiseux, Nicolas et al. (2006) Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement. FASEB J 20:661-9
Wu, Yaojiong; Ip, James E; Huang, Jing et al. (2006) Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium. Circ Res 99:315-22
Pachori, Alok S; Melo, Luis G; Zhang, Lunan et al. (2006) Chronic recurrent myocardial ischemic injury is significantly attenuated by pre-emptive adeno-associated virus heme oxygenase-1 gene delivery. J Am Coll Cardiol 47:635-43
Mirotsou, Maria; Dzau, Victor J; Pratt, Richard E et al. (2006) Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy. Physiol Genomics 27:86-94
Liu, Xiaoli; Pachori, Alok S; Ward, Christopher A et al. (2006) Heme oxygenase-1 (HO-1) inhibits postmyocardial infarct remodeling and restores ventricular function. FASEB J 20:207-16
Cunha-Neto, Edecio; Dzau, Victor J; Allen, Paul D et al. (2005) Cardiac gene expression profiling provides evidence for cytokinopathy as a molecular mechanism in Chagas' disease cardiomyopathy. Am J Pathol 167:305-13
Gnecchi, Massimiliano; He, Huamei; Liang, Olin D et al. (2005) Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells. Nat Med 11:367-8

Showing the most recent 10 out of 193 publications